Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12573106 | 1.00 | MAPK1 (0.52) | MAPK1CYP3A4MAPTTHRBMAPK14 | |
| SCHEMBL12573110 | 0.96 | MAPK1 (0.51) | MAPK1CYP3A4MAPTTHRBMAPK14 | |
| SCHEMBL15159451 | 0.91 | CYP3A4 (0.44) | MAPK1CYP3A4MAPTTHRBMAPK14 | |
| SCHEMBL12573077 | 0.91 | CYP3A4 (0.44) | MAPK1CYP3A4MAPTTHRBMAPK14 | |
| SCHEMBL13829594 | 0.81 | MAPK1 (0.52) | MAPK1CYP3A4MAPTTHRBMAPK14 | |
| SCHEMBL13829393 | 0.81 | MAPK1 (0.52) | MAPK1CYP3A4MAPTTHRBMAPK14 | |
| SCHEMBL12633131 | 0.81 | CYP3A4 (0.56) | MAPK1CYP3A4MAPTTHRBMAPK14 | |
| SCHEMBL12633132 | 0.81 | CYP3A4 (0.56) | MAPK1CYP3A4MAPTTHRBMAPK14 | |
| SCHEMBL13829573 | 0.80 | MAPK1 (0.52) | MAPK1CYP3A4MAPTTHRBMAPK14 | |
| SCHEMBL12573100 | 0.76 | ALDH1A1 (0.41) | CYP3A4MAPTGAAACHEABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501970-B2 | Method for the preparation of C-4 coupled flavonoids, proanthocyanidins and analogues thereof | UNIVERSITY OF THE FREE STATE (ZA) | 2013-08-06 | — | — | US | disclosed |
| US-20110160467-A1 | Method for the Preparation of C-4 Coupled Flavonoids, Proanthocyanidins and Analogues Thereof | UNIVERSITY OF THE FREE STATE (ZA) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160467-A1 | Method for the Preparation of C-4 Coupled Flavonoids, Proanthocyanidins and Analogues Thereof | C9, PROC, MLN | MAPK1 3038/4885CYP3A4 26/4885MAPT 2729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.