Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS9 | O00182 | 6/20 | 0.57 |
| ▸ | LGALS1 | P09382 | 6/20 | 0.57 |
| ▸ | LGALS3 | P17931 | 6/20 | 0.57 |
| ▸ | LGALS7; LGALS7B | P47929 | 5/20 | 0.57 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.43 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.37 |
| ▸ | SELP | P16109 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12136352 | 0.91 | LGALS3 (0.64) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8 | |
| SCHEMBL18942028 | 0.88 | LGALS9 (0.62) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8 | |
| SCHEMBL9116172 | 0.86 | LGALS9 (0.60) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8 | |
| SCHEMBL17154133 | 0.85 | LGALS3 (0.60) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8 | |
| SCHEMBL17154143 | 0.85 | LGALS3 (0.60) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8 | |
| SCHEMBL22821460 | 0.84 | POLB (0.48) | LGALS9LGALS1LGALS3LGALS7; LGALS7BCA12 | |
| SCHEMBL12585272 | 0.83 | LGALS9 (0.42) | LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL18067750 | 0.82 | LGALS9 (0.44) | LGALS9LGALS1LGALS3LGALS7; LGALS7BCA12 | |
| SCHEMBL27421786 | 0.82 | LGALS9 (0.43) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8 | |
| SCHEMBL19726119 | 0.82 | LGALS3 (0.54) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150166594-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-06-18 | — | — | US | disclosed |
| US-20110136759-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166594-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | MSN, MGAM, NISCH | LGALS9 4262/4885LGALS1 4621/4885LGALS3 4497/4885 |
| US-20110136759-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | MSN, MGAM, NISCH | LGALS9 4262/4885LGALS1 4621/4885LGALS3 4497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.