Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.57 |
| ▸ | CCR5 | P51681 | 3/20 | 0.57 |
| ▸ | CCR8 | P51685 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 7/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15024091 | 0.92 | KDM4E (0.67) | CCR1CCR5CCR8KDM4ETP53 | |
| SCHEMBL2989004 | 0.89 | CTRC (0.50) | CCR1CCR5CCR8L3MBTL1HTT | |
| SCHEMBL4367769 | 0.89 | KDM4E (0.62) | CCR1CCR5CCR8KDM4ETP53 | |
| SCHEMBL31635769 | 0.89 | KDM4E (0.62) | CCR1CCR5CCR8KDM4ETP53 | |
| SCHEMBL1991845 | 0.87 | KDM4E (0.64) | CCR1CCR5CCR8KDM4ETP53 | |
| SCHEMBL29260547 | 0.87 | CCR1 (0.70) | CCR1CCR5CCR8KDM4ETP53 | |
| SCHEMBL699036 | 0.87 | CCR1 (0.70) | CCR1CCR5CCR8KDM4ETP53 | |
| SCHEMBL30063905 | 0.87 | CCR1 (0.70) | CCR1CCR5CCR8KDM4ETP53 | |
| SCHEMBL31327467 | 0.85 | KDM4E (0.67) | CCR1CCR5CCR8KDM4ETP53 | |
| SCHEMBL1991759 | 0.84 | KDM4E (0.56) | CCR1CCR5CCR8KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019241873-A1 | METAL CONTAINING PRODUCTS AND COMPOSITIONS TO INDUCE IMMUNOGENIC CELL DEATH AND USES THEREOF | CUPROUS PHARMACEUTICALS INC. (CA) | 2019-12-26 | — | — | WO | disclosed |
| US-20130224624-A1 | PROTON EXCHANGE MEMBRANES | RENO (US) | 2013-08-29 | — | — | US | disclosed |
| US-20110033776-A1 | PROTON EXCHANGE MEMBRANES | Board of regents of the Nevada System of Higher Education, on Behalf of the University of | 2011-02-10 | — | — | US | disclosed |
| WO-2009142604-A1 | POLYMER ENCAPSULATED PARTICLES AS SURFACE ENHANCED RAMAN SCATTERING PROBES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2009-11-26 | — | — | WO | disclosed |