SCHEMBL12587635

SCHEMBL12587635

C=C(C)C1CCOC(C)C1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.31
LMNA P02545 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15712097 1.00 CYP2C19 (0.31) CYP2C19LMNAKDM4EALDH1A1
SCHEMBL27149389 0.78
SCHEMBL1413457 0.74 GABRR1 (0.36) CYP2C19LMNA
SCHEMBL25773481 0.74 EPHX1 (0.34)
SCHEMBL9441 0.72 SMN1; SMN2 (0.34) KDM4E
SCHEMBL30801614 0.72 NOS2 (0.42)
Hydrochloric Acid SCHEMBL4621413 0.71 SMN1; SMN2 (0.33) KDM4E
SCHEMBL18869616 0.71 DPP4 (0.33)
SCHEMBL24993959 0.70 PDK1 (0.36) ALDH1A1
Methyl Alcohol SCHEMBL22770521 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2314634-B1 EPOXY-GROUP-CONTAINING COPOLYMER, EPOXY (METH)ACRYLATE COPOLYMER USING SAME, AND PROCESSES FOR PRODUCING THE COPOLYMERS SHOWA DENKO KK (JP) 2014-05-07 EP disclosed
EP-2109635-B1 ORGANOSILICONE COMPOSITIONS AND METHODS FOR PREPARING THEM MOMENTIVE PERFORMANCE MAT INC (US) 2012-11-07 EP disclosed
US-20110144279-A1 EPOXY GROUP-CONTAINING COPOLYMER, EPOXY (METH)ACRYLATE COPOLYMER USING THE SAME AND THEIR PRODUCTION PROCESSES SHOWA DENKO K.K. (JP) 2011-06-16 US disclosed
EP-2314634-A1 EPOXY-GROUP-CONTAINING COPOLYMER, EPOXY (METH)ACRYLATE COPOLYMER USING SAME, AND PROCESSES FOR PRODUCING THE COPOLYMERS Showa Denko K.K. (JP) 2011-04-27 EP disclosed
US-7851548-B2 made from epoxy-functional siloxanes and epoxy-functional polyalkylene oxides, with linkages that include optionally quaternized amine groups; textile enhancers, fabric softeners, hair conditioners; low viscosity is obtained through the absence of H-bonding association with pendant hydroxyl groups MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-12-14 US disclosed
US-20100069651-A1 PROCESS FOR PRODUCTION OF DELTA-9-TETRAHYDROCANNABINOL ALBANY MOLECULAR RESEARCH, INC. (US) 2010-03-18 US disclosed
US-20090274643-A1 Low viscosity, high molecular weight linear random-block silicone polyalkyleneoxide copolymers MOMENTIVE PERFORMANCE MATERIALS INC. 2009-11-05 US disclosed
WO-2009067100-A1 ORGANOSILICONE COMPOSITIONS AND METHODS FOR PREPARING THEM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-05-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069651-A1 PROCESS FOR PRODUCTION OF DELTA-9-TETRAHYDROCANNABINOL CNR2, CNR1, HRH4 CYP2C19 417/4885LMNA 3504/4885KDM4E 2374/4885
US-20090274643-A1 Low viscosity, high molecular weight linear random-block silicone polyalkyleneoxide copolymers POLH, POLB, PCNA CYP2C19 3596/4885LMNA 2172/4885KDM4E 1193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.