SCHEMBL12587770

SCHEMBL12587770

COc1ccc(C(=O)c2ccc(CO)cc2)c(CO)c1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.46
LMNA P02545 3/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPT P10636 7/20 0.46
KDM4E B2RXH2 3/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
HPGD P15428 2/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP3A4 P08684 1/20 0.46
RECQL P46063 1/20 0.46
HTT P42858 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
NPC1 O15118 1/20 0.43
ALOX15 P16050 2/20 0.43
KMT2A Q03164 1/20 0.42
PDE4D Q08499 3/20 0.41
ACHE P22303 1/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2620569 0.88 MAPT (0.48) MAPK1LMNASMN1; SMN2MAPTKDM4E
SCHEMBL12587771 0.87 MAPT (0.57) MAPK1LMNASMN1; SMN2MAPTKDM4E
SCHEMBL15889632 0.86 SRD5A2 (0.39) MAPK1LMNASMN1; SMN2MAPTKDM4E
SCHEMBL30023021 0.77 MAPT (0.48) MAPK1LMNASMN1; SMN2MAPTKDM4E
SCHEMBL28349799 0.75 MAPT (0.57) MAPK1LMNASMN1; SMN2MAPTKDM4E
SCHEMBL30022921 0.74 PLK1 (0.46) MAPK1LMNASMN1; SMN2MAPTKDM4E
SCHEMBL16265253 0.74 CYP1A2 (0.73) LMNAMAPTHPGDALDH1A1CYP3A4
SCHEMBL15889633 0.72 MAPT (0.47) MAPK1LMNASMN1; SMN2MAPTKDM4E
SCHEMBL14194044 0.72 CYP1A2 (0.54) LMNAHPGDALDH1A1CYP3A4HTT
SCHEMBL15947113 0.72 ALDH1A1 (0.78) LMNAMAPTKDM4EHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9944730-B2 Polymers derived from norbornadiene and maleic anhydride and use thereof PROMERUS, LLC (US) 2018-04-17 US disclosed
US-9932432-B2 Polymers of maleimide and cycloolefinic monomers as permanent dielectric materials PROMERUS, LLC (US) 2018-04-03 US disclosed
US-20180044449-A1 POLYMERS DERIVED FROM NORBORNADIENE AND MALEIC ANHYDRIDE AND USE THEREOF PROMERUS, LLC (US) 2018-02-15 US disclosed
US-20180030189-A1 NADIC ANHYDRIDE POLYMERS AND PHOTOSENSITIVE COMPOSITIONS DERIVED THEREFROM PROMERUS, LLC (US) 2018-02-01 US disclosed
US-9834627-B2 Polymers derived from norbornadiene and maleic anhydride and use thereof PROMERUS, LLC (US) 2017-12-05 US disclosed
US-20170190810-A1 POLYMERS DERIVED FROM NORBORNADIENE AND MALEIC ANHYDRIDE AND USE THEREOF PROMERUS, LLC (US) 2017-07-06 US disclosed
US-20170174807-A1 POLYMER, PHOTOSENSITIVE RESIN COMPOSITION, AND ELECTRONIC DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2017-06-22 US disclosed
US-20170097566-A1 FLUORINE FREE PHOTOPATTERNABLE PHENOL FUNCTIONAL GROUP CONTAINING POLYMER COMPOSITIONS SUMITOMO BAKELITE CO., LTD. (JP) 2017-04-06 US disclosed
US-20170088672-A1 POLYMER, PHOTOSENSITIVE RESIN COMPOSITION, AND ELECTRONIC DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2017-03-30 US disclosed
US-9527943-B2 Polymer, photosensitive resin composition and electronic device SUMITOMO BAKELITE CO., LTD. (JP) 2016-12-27 US disclosed
US-9366956-B2 Self-imageable layer forming polymer and compositions thereof PROMERUS, LLC (US) 2016-06-14 US disclosed
US-9261782-B2 Maleimide containing cycloolefinic polymers and applications thereof PROMERUS, LLC (US) 2016-02-16 US disclosed
US-20150252132-A1 POLYMER, PHOTOSENSITIVE RESIN COMPOSITION AND ELECTRONIC DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2015-09-10 US disclosed
US-20140205948-A1 SELF-IMAGEABLE LAYER FORMING POLYMER AND COMPOSITIONS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2014-07-24 US disclosed
US-8715900-B2 Self-imageable layer forming polymer and compositions thereof PROMERUS, LLC (US) 2014-05-06 US disclosed
US-20140087293-A1 MALEIMIDE CONTAINING CYCLOOLEFINIC POLYMERS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2014-03-27 US disclosed
US-20130280654-A1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, PROTECTIVE FILM, INSULATING FILM, AND SEMICONDUCTOR DEVICE AND DISPLAY DEVICE INCLUDING THE CURED FILM SUMITOMO BAKELITE CO (JP) 2013-10-24 US disclosed
US-8492469-B2 Positive-type photosensitive resin composition, cured film, protective film, insulating film, and semiconductor device and display device including the cured film SUMITOMO BAKELITE CO., LTD. (JP) 2013-07-23 US disclosed
US-20130017488-A1 Self-Imageable Layer Forming Polymer and Compositions Thereof PROMERUS LLC (US) 2013-01-17 US disclosed
US-20110136952-A1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, PROTECTIVE FILM, INSULATING FILM, AND SEMICONDUCTOR DEVICE AND DISPLAY DEVICE INCLUDING THE CURED FILM SUMITOMO BAKELITE CO., LTD. (JP) 2011-06-09 US disclosed