Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524775 | 0.84 | SLC6A3 (0.38) | SLC18A3L3MBTL1SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL28374990 | 0.83 | SLC18A3 (0.44) | SLC18A3SLC6A3SLC6A4SLC6A2CACNA1B | |
| SCHEMBL28374988 | 0.83 | SLC18A3 (0.44) | SLC18A3SLC6A3SLC6A4SLC6A2CACNA1B | |
| SCHEMBL13707303 | 0.82 | DRD2 (0.53) | SLC18A3L3MBTL1DRD4HTR2AHTR2C | |
| SCHEMBL3493992 | 0.82 | SLC18A3 (0.44) | SLC18A3SLC6A3SLC6A4SLC6A2CACNA1F | |
| SCHEMBL2050725 | 0.82 | SLC18A3 (0.44) | SLC18A3SLC6A3SLC6A4SLC6A2CACNA1F | |
| SCHEMBL28883791 | 0.82 | SLC18A3 (0.44) | SLC18A3SLC6A3SLC6A4SLC6A2CACNA1F | |
| SCHEMBL514845 | 0.82 | SLC18A3 (0.44) | SLC18A3SLC6A3SLC6A4SLC6A2CACNA1F | |
| SCHEMBL515189 | 0.82 | SLC18A3 (0.44) | SLC18A3SLC6A3SLC6A4SLC6A2CACNA1F | |
| SCHEMBL542243 | 0.82 | SLC18A3 (0.44) | SLC18A3SLC6A3SLC6A4SLC6A2CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956182-B2 | Process for preparing optically active alcohols | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2011-06-07 | — | — | US | disclosed |