SCHEMBL1259142

SCHEMBL1259142

CC(=CC(=O)O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.61
TDP1 Q9NUW8 1/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
SLC22A12 Q96S37 1/20 0.57
CES1 P23141 2/20 0.55
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CES2 O00748 1/20 0.53
SRD5A2 P31213 1/20 0.53
NR4A1 P22736 1/20 0.53
NR4A2 P43354 1/20 0.53
NR4A3 Q92570 1/20 0.53
TSHR P16473 1/20 0.52
ALDH1A1 P00352 1/20 0.52
NPC1 O15118 1/20 0.49
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3029025 1.00 MAPK1 (0.61) MAPK1TDP1MEN1KMT2ASLC22A12
SCHEMBL9609546 0.87 MAPK1 (0.63) MAPK1TDP1MEN1KMT2ACES1
SCHEMBL11102210 0.84 ALDH1A1 (0.59) MAPK1TDP1MEN1KMT2ACES1
SCHEMBL11102207 0.84 ALDH1A1 (0.59) MAPK1TDP1MEN1KMT2ACES1
SCHEMBL9010720 0.81 MAPK1 (0.56) MAPK1TDP1MEN1KMT2ASLC22A12
SCHEMBL5757238 0.80 ALDH1A1 (0.66) MEN1KMT2ASLC22A12CES1CES2
SCHEMBL5757234 0.80 ALDH1A1 (0.66) MEN1KMT2ASLC22A12CES1CES2
SCHEMBL2920013 0.80 ALDH1A1 (0.66) MEN1KMT2ASLC22A12CES1CES2
SCHEMBL3024537 0.79 ALDH1A1 (0.50) MAPK1TDP1MEN1KMT2ASLC22A12
SCHEMBL3024541 0.79 ALDH1A1 (0.50) MAPK1TDP1MEN1KMT2ASLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747059-A1 PERVAPORATION COMPOSITE MEMBRANES McMaster University (CA) 2007-01-31 EP claimed
US-20060000778-A1 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2006-01-05 US claimed
WO-2005102503-A1 PERVAPORATION COMPOSITE MEMBRANES MCMASTER UNIVERSITY (CA) 2005-11-03 WO claimed
US-4748161-A Triterpenyl esters of organic acids and hypolipidemic agents composed of them AMANO PHARMACEUTICAL CO., LTD. (JP) 1988-05-31 US claimed
EP-0166542-A2 Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them AMANO PHARMACEUTICAL CO., LTD. (JP) 1986-01-02 EP claimed
EP-2226192-B1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL 1987 LTD (IL) 2016-08-31 EP disclosed
EP-2226116-B1 Drying tube, preparation and use thereof ORIDION MEDICAL 1987 LTD (IL) 2016-04-20 EP disclosed
US-20150283519-A1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL 1987 LTD. (IL) 2015-10-08 US disclosed
US-9090766-B2 Drying substances, preparation and use thereof ORIDION MEDICAL 1987 LTD. (IL) 2015-07-28 US disclosed
US-9067035-B2 Drying substances, preparation and use thereof ORIDION MEDICAL (1987) LTD. (IL) 2015-06-30 US disclosed
US-20140230652-A1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL (1987) LTD. (IL) 2014-08-21 US disclosed
US-8764888-B2 Drying substances, preparation and use thereof ORIDION MEDICAL 1987 LTD. (IL) 2014-07-01 US disclosed
EP-0050977-B1 CARBOXAMIDE COMPOUNDS AS SRS-A ANTAGONISTS AND A PROCESS FOR PRODUCING SAME PFIZER INC. (US) 1983-09-14 EP disclosed
US-4343813-A ANTIANAPHYLACTIC AGENTS PFIZER INC. (US) 1982-08-10 US disclosed
US-4331683-A SENSITIZATION, ANTIALLERGENS PFIZER INC. (US) 1982-05-25 US disclosed
EP-0050977-A1 Carboxamide compounds as SRS-A antagonists and a process for producing same PFIZER INC. (US) 1982-05-05 EP disclosed
EP-0047119-A1 Carboxamide compounds as SRS-A antagonists, pharmaceutical compositions containing them, processes for the preparation, and intermediates useful therein PFIZER INC. (US) 1982-03-10 EP disclosed
US-4296129-A ANTIAASTHMATIC INHIBITOR OF SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS PFIZER, INC. (US) 1981-10-20 US disclosed
US-4296120-A ANTIANAPHYLACTIC PFIZER INC. (US) 1981-10-20 US disclosed
US-4182897-A ENZYME INHIBITORS FOR PROTEOLYTIC ENZYMES TORII & CO., LTD. (JP) 1980-01-08 US disclosed