Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3024537 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRKMT2AMEN1 | |
| SCHEMBL3024539 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRKMT2AMEN1 | |
| SCHEMBL16971053 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRKMT2AMEN1 | |
| SCHEMBL9358690 | 0.82 | L3MBTL1 (0.57) | ALDH1A1TDP1TSHRKMT2AMEN1 | |
| SCHEMBL9551017 | 0.82 | KMT2A (0.55) | ALDH1A1TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL28713222 | 0.81 | KMT2A (0.47) | ALDH1A1TDP1TSHRKMT2AMEN1 | |
| SCHEMBL2371651 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRKMT2AMEN1 | |
| SCHEMBL33664 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRKMT2AMEN1 | |
| SCHEMBL30539159 | 0.80 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRKMT2AMEN1 | |
| SCHEMBL836536 | 0.80 | ALDH1A1 (0.60) | ALDH1A1TDP1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855300-B2 | Bis(trimethylsilyl)phenyl compound or salt thereof, and use thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2010-12-21 | — | — | US | disclosed |
| US-20100210591-A1 | BIS(TRIMETHYLSILYL)PHENYL COMPOUND OR SALT THEREOF, AND USE THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2010-08-19 | — | — | US | disclosed |
| EP-2202235-A1 | BIS(TRIMETHYLSILYL)PHENYL COMPOUND OR SALT THEREOF, AND USE THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210591-A1 | BIS(TRIMETHYLSILYL)PHENYL COMPOUND OR SALT THEREOF, AND USE THEREOF | RARA, RARB, RXRA | ALDH1A1 1156/4885TDP1 4309/4885TSHR 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.