Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514151 | 1.00 | SIGMAR1 (0.37) | SIGMAR1METAP2ALDH1A1BCHENPC1 | |
| SCHEMBL7519673 | 0.83 | ALDH1A1 (0.39) | SIGMAR1ALDH1A1HPGDTDP1HSD17B10 | |
| SCHEMBL14923342 | 0.80 | METAP2 (0.35) | SIGMAR1METAP2ALDH1A1BCHENPC1 | |
| SCHEMBL7519834 | 0.78 | ALDH1A1 (0.40) | SIGMAR1ALDH1A1HPGDTDP1HSD17B10 | |
| SCHEMBL7519855 | 0.77 | GRM2 (0.41) | ALDH1A1HPGDTDP1HSD17B10CASP3 | |
| Hydrochloric Acid SCHEMBL10421626 | 0.76 | ALDH1A1 (0.39) | SIGMAR1ALDH1A1HPGDTDP1HSD17B10 | |
| SCHEMBL15871759 | 0.76 | ALDH1A1 (0.35) | METAP2ALDH1A1BCHE | |
| SCHEMBL12409411 | 0.74 | ALDH1A1 (0.36) | METAP2ALDH1A1HPGDTDP1HSD17B10 | |
| SCHEMBL10305525 | 0.74 | ALDH1A1 (0.36) | METAP2ALDH1A1HPGDTDP1HSD17B10 | |
| SCHEMBL7535882 | 0.74 | ALDH1A1 (0.36) | METAP2ALDH1A1HPGDTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2335701-A1 | Heterocyclic aspartyl protease inhibitors | Schering Corporation (US) | 2011-06-22 | — | — | EP | disclosed |