Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | UQCRB | P14927 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288322 | 0.93 | ESR1 (0.56) | HSD11B1ELANEGAAPKMESR1 | |
| SCHEMBL12531593 | 0.90 | ELANE (0.59) | HSD11B1ELANEGAAPKMESR1 | |
| SCHEMBL12531631 | 0.90 | ELANE (0.59) | HSD11B1ELANEGAAPKMESR1 | |
| SCHEMBL12199023 | 0.90 | ELANE (0.59) | HSD11B1ELANEGAAPKMESR1 | |
| SCHEMBL12676446 | 0.90 | ELANE (0.59) | HSD11B1ELANEGAAPKMESR1 | |
| SCHEMBL12676698 | 0.90 | ELANE (0.59) | HSD11B1ELANEGAAPKMESR1 | |
| SCHEMBL12676583 | 0.90 | ELANE (0.59) | HSD11B1ELANEGAAPKMESR1 | |
| SCHEMBL12451153 | 0.89 | PKM (0.65) | HSD11B1ELANEGAAPKMESR1 | |
| SCHEMBL10052278 | 0.88 | HSD11B1 (0.51) | HSD11B1ELANEGAAPKMESR1 | |
| SCHEMBL19392509 | 0.86 | HSD11B1 (0.47) | HSD11B1ELANEGAAPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3577164-B1 | POLYARYLENE ETHER SULFONE COMPRISING NAPHTHALIC ACID ANHYDRIDE ENDGROUPS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |
| EP-2358787-B1 | METHOD FOR PREPARING A REACTIVE POLYARYLENE ETHER | BASF SE (DE) | 2013-01-09 | — | — | EP | disclosed |
| EP-2336220-A1 | Improved blends of polyarylene ethers and polyarylene sulphides | BASF SE (DE) | 2011-06-22 | — | — | EP | disclosed |
| EP-1681311-B1 | Branched sulfonated polyarylether | BASF AG (DE) | 2007-11-28 | — | — | EP | disclosed |