Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | BAX | Q07812 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288322 | 0.94 | ESR1 (0.56) | HSD11B1ESR2ESR1HTTSMN1; SMN2 | |
| SCHEMBL7929093 | 0.91 | ESR1 (0.60) | HSD11B1ESR2ESR1GAAPKM | |
| SCHEMBL12596507 | 0.88 | HSD11B1 (0.50) | HSD11B1ESR2ESR1HTTSMN1; SMN2 | |
| SCHEMBL12451153 | 0.88 | PKM (0.65) | HSD11B1ESR2ESR1HTTSMN1; SMN2 | |
| SCHEMBL14216928 | 0.86 | HSD11B1 (0.56) | HSD11B1ESR2ESR1HTTSMN1; SMN2 | |
| SCHEMBL24445611 | 0.85 | LTA4H (0.63) | ESR2ESR1HTTSMN1; SMN2GAA | |
| SCHEMBL24445604 | 0.85 | LTA4H (0.63) | ESR2ESR1HTTSMN1; SMN2GAA | |
| SCHEMBL18678670 | 0.85 | LTA4H (0.63) | ESR2ESR1HTTSMN1; SMN2GAA | |
| SCHEMBL7938159 | 0.85 | LTA4H (0.63) | ESR2ESR1HTTSMN1; SMN2GAA | |
| SCHEMBL14288325 | 0.83 | BCL2L1 (0.44) | HSD11B1ESR2ESR1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3850033-B1 | POLYARYLENE ETHER SULFONE | BASF SE (DE) | 2023-05-17 | — | — | EP | disclosed |
| EP-3850032-B1 | POLYARYLENE ETHER | BASF SE (DE) | 2022-05-25 | — | — | EP | disclosed |
| US-8110639-B2 | Transparent and flame retardant polysulfone compositions | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2012-02-07 | — | — | US | disclosed |
| US-20090283476-A1 | Transparent and flame retardant polysulfone compositions | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2009-11-19 | — | — | US | disclosed |