Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 1.00 |
| ▸ | AGTR2 | P50052 | 5/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12465549 | 0.84 | AGTR1 (0.75) | AGTR1AGTR2 | |
| SCHEMBL7622112 | 0.84 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL29486817 | 0.84 | AGTR1 (0.72) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL7841670 | 0.83 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL29549716 | 0.82 | AGTR1 (0.69) | AGTR1AGTR2 | |
| SCHEMBL2834891 | 0.81 | GP6 (0.77) | AGTR1AGTR2 | |
| SCHEMBL9312828 | 0.81 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL13449213 | 0.81 | GP6 (0.78) | AGTR1AGTR2 | |
| SCHEMBL2834888 | 0.80 | GP6 (0.75) | AGTR1AGTR2 | |
| SCHEMBL20257387 | 0.80 | AGTR1 (0.81) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569528-B2 | Process for the preparation of tetrazole derivatives from organo boron and organo aluminium azides | NOVARTIS AG (CH) | 2013-10-29 | — | — | US | disclosed |
| US-20120330026-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES | NOVARTIS AG (CH) | 2012-12-27 | — | — | US | disclosed |
| US-7943647-B2 | Process for the preparation of tetrazole derivatives from organo aluminium azides | NOVARTIS AG (CH) | 2011-05-17 | — | — | US | disclosed |
| US-7943647-B2 | Process for the preparation of tetrazole derivatives from organo aluminium azides | NOVARTIS AG (CH) | 2011-05-17 | — | — | US | disclosed |
| US-20070043098-A1 | Process for the preparation of tetrazole derivatives from organo boron and organo aluminium azides | NOVARTIS PHARMACEUTICALS CORPORATION | 2007-02-22 | — | — | US | disclosed |
| US-20070043098-A1 | Process for the preparation of tetrazole derivatives from organo boron and organo aluminium azides | NOVARTIS PHARMACEUTICALS CORPORATION | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043098-A1 | Process for the preparation of tetrazole derivatives from organo boron and organo aluminium azides | ABL1, TBCA, TBC1D5 | AGTR1 2005/4885AGTR2 1882/4885 |
| US-20120330026-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES | ABL1, TBCA, TBC1D5 | AGTR1 2005/4885AGTR2 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.