Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14191139 | 0.74 | — | — | |
| SCHEMBL4826004 | 0.73 | — | — | |
| SCHEMBL19526243 | 0.71 | PARP1 (0.35) | PARP1PARP15PARP10 | |
| SCHEMBL22281750 | 0.71 | PARP1 (0.35) | PARP1PARP15PARP10 | |
| SCHEMBL17865331 | 0.70 | PRKCA (0.47) | — | |
| SCHEMBL20344409 | 0.69 | SHBG (0.30) | — | |
| SCHEMBL3287967 | 0.68 | ALDH1A1 (0.44) | — | |
| SCHEMBL19816450 | 0.68 | PPM1B (0.41) | — | |
| SCHEMBL19816460 | 0.68 | PPM1B (0.41) | — | |
| SCHEMBL4857880 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114937-B1 | PHENOTHIAZIN DERIVATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS PHARMACEUTICALS | SANOFI AVENTIS (FR) | 2011-06-29 | — | — | EP | disclosed |