Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 10/20 | 0.78 |
| ▸ | MAPK12 | P53778 | 10/20 | 0.78 |
| ▸ | MAPK11 | Q15759 | 10/20 | 0.78 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.78 |
| ▸ | GCGR | P47871 | 6/20 | 0.78 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | RAF1 | P04049 | 4/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.55 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883313 | 0.93 | MAPK13 (0.65) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL11176392 | 0.89 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL28158811 | 0.82 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL12561692 | 0.82 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL14045570 | 0.82 | MAPK13 (0.85) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL6469543 | 0.82 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL2650068 | 0.82 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL12561695 | 0.81 | KDM4E (0.80) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL28789580 | 0.81 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL5074753 | 0.81 | MAPK13 (0.83) | MAPK13MAPK12MAPK11MAPK14GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152337-A1 | 2,4,5-TRISUBSTITUTED IMIDAZOLES AND THEIR USE AS ANTI-MICROBIAL AGENTS | LORUS THERAPEUTICS INC. (CA) | 2011-06-23 | — | — | US | disclosed |
| US-7884120-B2 | microbiocides such as 2-(2-methyl-1H-indol-3-yl)-3a,11b-dihydro-1H-phenanthro[9,10-d]imidazole; bactericides; fungicides | LORUS THERAPEUTICS INC. (CA) | 2011-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152337-A1 | 2,4,5-TRISUBSTITUTED IMIDAZOLES AND THEIR USE AS ANTI-MICROBIAL AGENTS | IDO2, ERG28, IL4 | MAPK13 3668/4885MAPK12 3161/4885MAPK11 3626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.