SCHEMBL12601671

SCHEMBL12601671

CCSc1c(Cl)ccc(C(=O)c2c(C3CC3)nn(C)c2O)c1C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1779277 0.92 CRHR1 (0.30)
SCHEMBL12601688 0.91 MPO (0.31)
SCHEMBL12601685 0.89
SCHEMBL12601670 0.88 PDE4B (0.31)
SCHEMBL12601675 0.85 HCRTR1 (0.33)
SCHEMBL12601677 0.85
SCHEMBL12601687 0.82 MPO (0.31)
SCHEMBL8341103 0.82 MGLL (0.32) CNR1CNR2
SCHEMBL19075100 0.81
SCHEMBL12601679 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2167473-B1 3-CYCLOPROPYL-4-(3-THIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BAYER IP GMBH (DE) 2017-07-05 EP disclosed
US-7943551-B2 3-cyclopropyl-4-(3-thiobenzoyl) pyrazoles and their use as herbicides BAYER CROPSCIENCE AG (DE) 2011-05-17 US disclosed
US-7943551-B2 3-cyclopropyl-4-(3-thiobenzoyl) pyrazoles and their use as herbicides BAYER CROPSCIENCE AG (DE) 2011-05-17 US disclosed
WO-2008151719-A2 3-CYCLOPROPYL-4-(3-THIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2008-12-18 WO disclosed
US-20080305956-A1 3-Cyclopropyl-4-(3-Thiobenzoyl) Pyrazoles And Their Use as Herbicides BAYER CROPSCIENCE AG (US) 2008-12-11 US disclosed
US-20080305956-A1 3-Cyclopropyl-4-(3-Thiobenzoyl) Pyrazoles And Their Use as Herbicides BAYER CROPSCIENCE AG (US) 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080305956-A1 3-Cyclopropyl-4-(3-Thiobenzoyl) Pyrazoles And Their Use as Herbicides TH, GLRX3, DDT CNR1 1084/4885CNR2 990/4885PTGDR2 1096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.