Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12601675 | 0.89 | HCRTR1 (0.33) | HCRTR1HCRTR2XPO1 | |
| SCHEMBL1781054 | 0.85 | HCRTR1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL12601685 | 0.84 | — | — | |
| SCHEMBL27516520 | 0.83 | XPO1 (0.33) | HCRTR1HCRTR2LRRK2XPO1 | |
| SCHEMBL12601682 | 0.82 | — | — | |
| SCHEMBL19893749 | 0.79 | RORC (0.33) | HCRTR1HCRTR2XPO1 | |
| SCHEMBL8341676 | 0.78 | SLC6A9 (0.38) | — | |
| SCHEMBL418823 | 0.77 | — | — | |
| SCHEMBL19075100 | 0.77 | — | — | |
| SCHEMBL12601671 | 0.76 | CNR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167473-B1 | 3-CYCLOPROPYL-4-(3-THIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | BAYER IP GMBH (DE) | 2017-07-05 | — | — | EP | disclosed |
| US-7943551-B2 | 3-cyclopropyl-4-(3-thiobenzoyl) pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2011-05-17 | — | — | US | disclosed |
| US-7943551-B2 | 3-cyclopropyl-4-(3-thiobenzoyl) pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2011-05-17 | — | — | US | disclosed |
| US-20080305956-A1 | 3-Cyclopropyl-4-(3-Thiobenzoyl) Pyrazoles And Their Use as Herbicides | BAYER CROPSCIENCE AG (US) | 2008-12-11 | — | — | US | disclosed |
| US-20080305956-A1 | 3-Cyclopropyl-4-(3-Thiobenzoyl) Pyrazoles And Their Use as Herbicides | BAYER CROPSCIENCE AG (US) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305956-A1 | 3-Cyclopropyl-4-(3-Thiobenzoyl) Pyrazoles And Their Use as Herbicides | TH, GLRX3, DDT | HCRTR1 413/4885HCRTR2 821/4885LRRK2 3916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.