Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259884 | 0.85 | CTSK (0.34) | CTSSCTSK | |
| SCHEMBL14688156 | 0.85 | MEN1 (0.34) | CTSSCTSK | |
| SCHEMBL1258946 | 0.85 | MEN1 (0.34) | CTSSCTSK | |
| SCHEMBL15876359 | 0.81 | CTSS (0.30) | CTSSCTSK | |
| SCHEMBL1259908 | 0.75 | CTSK (0.38) | CTSSCTSK | |
| SCHEMBL27911439 | 0.74 | MEN1 (0.34) | CTSSCTSK | |
| SCHEMBL1260235 | 0.74 | MEN1 (0.33) | — | |
| SCHEMBL29437626 | 0.71 | CTSS (0.32) | CTSSCTSK | |
| SCHEMBL30365173 | 0.71 | CTSS (0.32) | CTSSCTSK | |
| SCHEMBL9242626 | 0.68 | GPR84 (0.42) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8617864-B2 | Polynucleotides encoding ketoreductases for producing stereoisomerically pure statins and synthetic intermediates therefor | CODEXIS, INC. (US) | 2013-12-31 | — | — | US | disclosed |
| US-20130040364-A1 | POLYNUCLEOTIDES ENCODING KETOREDUCTASES FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | CODEXIS, INC. (US) | 2013-02-14 | — | — | US | disclosed |
| US-8273547-B2 | Engineered ketoreductases and methods for producing stereoisomerically pure statins | CODEXIS, INC. (US) | 2012-09-25 | — | — | US | disclosed |
| US-20110195465-A1 | Compositions and Methods for Producing Stereoisomerically Pure Statins and Synthetic Intermediates Therefor | CODEXIS, INC. (US) | 2011-08-11 | — | — | US | disclosed |
| US-7879585-B2 | Ketoreductases of Saccharomyces cerevisiae; host cells | CODEXIS, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-20080248539-A1 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | CODEXIS, INC. (US) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080248539-A1 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | COASY, FAR1, HMGCR | CTSS 2003/4885CTSK 3212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.