Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | FBP1 | P09467 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19520022 | 0.94 | KMO (0.36) | MEN1RAB9AKMT2AHDAC8FBP1 | |
| SCHEMBL14731220 | 0.91 | RAB9A (0.44) | MEN1RAB9AKMT2AKMOPTPN5 | |
| SCHEMBL9927376 | 0.86 | FBP1 (0.41) | MEN1RAB9AKMT2AFBP1CA2 | |
| SCHEMBL11991069 | 0.85 | MEN1 (0.45) | MEN1RAB9AKMT2AFBP1KMO | |
| SCHEMBL11991065 | 0.84 | MEN1 (0.41) | MEN1RAB9AKMT2AFBP1CA2 | |
| SCHEMBL10039221 | 0.82 | HDAC8 (0.50) | HDAC8KMOPTPN1PTPN5CA2 | |
| SCHEMBL11991100 | 0.81 | MEN1 (0.54) | MEN1RAB9AKMT2AHDAC8FBP1 | |
| SCHEMBL22634016 | 0.80 | HDAC8 (0.48) | HDAC8KMOPTPN1PTPN5CA2 | |
| SCHEMBL11991059 | 0.80 | HDAC8 (0.48) | HDAC8KMOPTPN1PTPN5CA2 | |
| SCHEMBL14023425 | 0.80 | KDM4E (0.50) | RAB9AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748878-B1 | ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2020-04-01 | — | — | EP | disclosed |
| US-9735385-B2 | Organic electroluminescence device | MERCK PATENT GMBH (DE) | 2017-08-15 | — | — | US | disclosed |
| US-9735385-B2 | Organic electroluminescence device | MERCK PATENT GMBH (DE) | 2017-08-15 | — | — | US | disclosed |
| US-20110108818-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | US | disclosed |
| US-20110108818-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | US | disclosed |