Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21848864 | 0.72 | CYP2A6 (0.59) | CYP2A6GPR35CYP2B6CYP2E1MEN1 | |
| SCHEMBL11937865 | 0.72 | LRRK2 (0.51) | CYP2A6GPR35IMPDH2CYP2B6CYP2E1 | |
| SCHEMBL1126765 | 0.72 | ACMSD (0.50) | CYP2A6GPR35BTKCYP2B6CYP2E1 | |
| SCHEMBL1989501 | 0.71 | HSD17B10 (0.56) | MEN1USP2MAPTALOX15KMT2A | |
| SCHEMBL6320052 | 0.71 | CYP2A6 (0.52) | CYP2A6GPR35CYP2B6CYP2E1MAPT | |
| SCHEMBL2094933 | 0.70 | CYP2A6 (0.42) | CYP2A6GPR35BTKCYP2B6CYP2E1 | |
| SCHEMBL10767146 | 0.68 | CYP2A6 (0.49) | CYP2A6GPR35BTKCYP2B6CYP2E1 | |
| SCHEMBL14003393 | 0.68 | CYP2A6 (0.53) | CYP2A6GPR35IMPDH2BTKCYP2B6 | |
| SCHEMBL27465618 | 0.68 | PDCD1 (0.44) | BRD4CYP2A6GPR35CYP2B6CYP2E1 | |
| SCHEMBL22734811 | 0.68 | CYP2A6 (0.52) | CYP2A6GPR35IMPDH2CYP2B6CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943787-B2 | Preparation of pentafluorosulfanyl (SF5) heterocycles: pyrroles and thiophenes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2011-05-17 | — | — | US | disclosed |
| US-20110040103-A1 | PREPARATION OF PENTAFLUOROSULFANYL (SF5) HETEROCYCLES: PYRROLES AND THIOPHENES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110040103-A1 | PREPARATION OF PENTAFLUOROSULFANYL (SF5) HETEROCYCLES: PYRROLES AND THIOPHENES | SF3B5, SFXN3, CXCR5 | BRD4 902/4885CYP2A6 2913/4885GPR35 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.