Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3172447 | 0.80 | TSHR (0.50) | HPGDACHEBLMSIGMAR1CYP3A4 | |
| SCHEMBL12604279 | 0.78 | CES2 (0.48) | HPGDACHECYP3A4CYP2C9CYP2C19 | |
| Methyl Alcohol SCHEMBL27278041 | 0.76 | TSHR (0.46) | HPGDACHEBLMSIGMAR1CYP3A4 | |
| SCHEMBL9525142 | 0.75 | MAPT (0.41) | HPGDACHESIGMAR1CYP3A4CYP2C9 | |
| SCHEMBL946095 | 0.75 | TSHR (0.48) | HPGDACHEBLMSIGMAR1CYP3A4 | |
| SCHEMBL1892160 | 0.73 | TSHR (0.47) | HPGDACHEBLMSIGMAR1CYP3A4 | |
| SCHEMBL11003826 | 0.71 | CYP3A4 (0.57) | HPGDACHEBLMCYP3A4CYP2C9 | |
| SCHEMBL23611618 | 0.71 | NOTUM (0.33) | HPGDACHECYP3A4POLBALDH1A1 | |
| SCHEMBL252026 | 0.70 | HPGD (0.79) | HPGDACHEBLMSIGMAR1POLB | |
| SCHEMBL7129676 | 0.70 | HPGD (0.79) | HPGDACHEBLMSIGMAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943787-B2 | Preparation of pentafluorosulfanyl (SF5) heterocycles: pyrroles and thiophenes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2011-05-17 | — | — | US | disclosed |
| US-20110040103-A1 | PREPARATION OF PENTAFLUOROSULFANYL (SF5) HETEROCYCLES: PYRROLES AND THIOPHENES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110040103-A1 | PREPARATION OF PENTAFLUOROSULFANYL (SF5) HETEROCYCLES: PYRROLES AND THIOPHENES | SF3B5, SFXN3, CXCR5 | HPGD 2820/4885ACHE 3378/4885BLM 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.