Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892160 | 0.98 | TSHR (0.47) | TSHRRAB9AL3MBTL1HPGDCES2 | |
| Methyl Alcohol SCHEMBL27278041 | 0.95 | TSHR (0.46) | TSHRRAB9AL3MBTL1HPGDCES2 | |
| SCHEMBL27386714 | 0.89 | L3MBTL1 (0.42) | TSHRRAB9AL3MBTL1HPGDCES2 | |
| SCHEMBL3895806 | 0.86 | TSHR (0.55) | TSHRRAB9ACES2CES1DAO | |
| SCHEMBL27639057 | 0.81 | UNG (0.50) | TSHRL3MBTL1HPGDDAONAPRT | |
| SCHEMBL31068112 | 0.79 | HPGD (0.52) | L3MBTL1HPGDCES2CES1GSK3B | |
| SCHEMBL6323112 | 0.79 | LMNA (0.52) | TSHRRAB9AHPGDALDH1A1P2RX4 | |
| SCHEMBL3172447 | 0.76 | TSHR (0.50) | TSHRRAB9AL3MBTL1HPGDCES2 | |
| SCHEMBL11277690 | 0.75 | ALDH1A1 (0.61) | L3MBTL1HPGDNAPRTALDH1A1MAPT | |
| SCHEMBL12604282 | 0.75 | HPGD (0.48) | TSHRHPGDCES2CES1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119080693-A | Quinoline compound of trifluoromethyl alkyl, synthetic method and antitumor application thereof | 遵义医科大学 | 2024-12-06 | — | — | CN | claimed |
| CN-109071563-A | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-109071548-A | It can be used for treating the pyrroles's benzimidazole derivative or its analog of especially cancer | 埃姆库瑞医药品有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-108033964-A | A kind of Pyridinylimidazoles and benzodiazepine propionate compound and its synthesis and application | 杭州奥默医药股份有限公司 | 2018-05-15 | — | — | CN | claimed |
| CN-107635986-A | Substituted quinoxaline derivatives | 赛尔维他股份公司 | 2018-01-26 | — | — | CN | claimed |
| CN-105039499-A | Preparation and application of fluorescence probe for detecting [gamma]-glutamyltransferase (GGT) in cancer cells | UNIV EAST CHINA SCIENCE & TECH | 2015-11-11 | — | — | CN | claimed |
| CN-103254109-B | Benzoyl pyrrole derivative and synthetic method thereof | UNIV SHANXI | 2015-01-28 | — | — | CN | claimed |
| CN-102584668-B | Method for preparing 2,3-dibromo-5-benzoyl pyrrole | SYNCHEM BENGBU TECHNOLOLY CO LTD | 2014-06-18 | — | — | CN | claimed |
| CN-103254109-A | Benzoyl pyrrole derivative and synthetic method thereof | UNIV SHANXI | 2013-08-21 | — | — | CN | claimed |
| CN-102584668-A | Method for preparing 2,3-dibromo-5-benzoyl pyrrole | SYNCHEM BENGBU TECHNOLOLY CO LTD | 2012-07-18 | — | — | CN | claimed |
| CN-101535324-A | Organic iridium compositions and their use in electronic devices | GEN ELECTRIC (US) | 2009-09-16 | — | — | CN | claimed |
| EP-2049555-A2 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2009-04-22 | — | — | EP | claimed |
| CN-101134740-A | Method for synthesizing ketorolac ammonia butanetriol key intermediate compound benzoyl pyrrole | ZHEJIANG INDUSTRY UNIVERSITY Z (CN) | 2008-03-05 | — | — | CN | claimed |
| EP-1529034-B1 | BENZOYLPYRAZOLONES SUBSTITUTED BY 3-AMINOCARBONYL | BAYER CROPSCIENCE AG (DE) | 2008-02-20 | — | — | EP | claimed |
| US-20080026249-A1 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | claimed |
| WO-2008014037-A2 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2008-01-31 | — | — | WO | claimed |
| US-20050267184-A1 | 3-Aminocarbonyl substituted benzoylpyrazolones | BAYER CROPSCIENCE GMBH (DE) | 2005-12-01 | — | — | US | claimed |
| US-20040072693-A1 | 3-aminocarbonyl substituted benzoylpyrazolones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-04-15 | — | — | US | claimed |
| CN-1337850-A | Amide derivatives for antiangiogenesis and/or antitumor | UNIV VANDERBILT (US) | 2002-02-27 | — | — | CN | claimed |
| CN-1295462-A | Peroral active agent suspension | BOEHRINGER INGEHEIM PHARMA KG (DE) | 2001-05-16 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072693-A1 | 3-aminocarbonyl substituted benzoylpyrazolones | CBR3, MT-CO3, CBR1 | TSHR 2038/4885RAB9A 2165/4885L3MBTL1 1048/4885 |
| US-20050267184-A1 | 3-Aminocarbonyl substituted benzoylpyrazolones | CBR3, CYCS, MT-CO2 | TSHR 1489/4885RAB9A 2894/4885L3MBTL1 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.