Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL3310615 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL16144857 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL15417972 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL1259377 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL2857167 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL14630991 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL1259419 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL15418012 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL37398 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL3312144 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046169-A1 | FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046169-A1 | FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF | ABL1, MAP4K2, MAP3K20 | ALDH1A1 2255/4885LMNA 3734/4885HSD17B10 2530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.