Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL3310615 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL16144857 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL15417972 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL1259377 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL2857167 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL14630991 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL1259419 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL15418012 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL1260460 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| Ethyl Acetate SCHEMBL3312144 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 514 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004186-A1 | MEK inhibiting compounds | PFIZER INC | 2005-01-06 | — | — | US | claimed |
| CN-118056833-A | Barbituric acid macrocyclic compound and preparation method and application thereof | 中国科学院化学研究所 | 2024-05-21 | — | — | CN | disclosed |
| US-20240158430-A1 | NOVEL COMPOUND OR SALT THEREOF, AND ANTITUMOR ACTIVATOR CONTAINING SAME AS ACTIVE INGREDIENT | AKITA UNIVERSITY (JP) | 2024-05-16 | — | — | US | disclosed |
| US-20240083899-A1 | PURINONE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-03-14 | — | — | US | disclosed |
| WO-2024043319-A1 | ANTIBODY-DRUG COMPLEX | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2024-02-29 | — | — | WO | disclosed |
| WO-2024013400-A1 | AGENT CONTAINING MALONIC ACID OR ITS DERIVATIVES FOR RESTORING METAL HOMEOSTASIS | OXFORD ANTIBIOTIC GROUP GMBH (AT) | 2024-01-18 | — | — | WO | disclosed |
| CN-116670126-A | Azaheteroaryl derivatives with EGFR inhibiting activity, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-08-29 | — | — | CN | disclosed |
| US-20230190698-A1 | BICYCLIC COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-06-22 | — | — | US | disclosed |
| US-11617733-B2 | Bicyclic compound and use thereof for medical purposes | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-04-04 | — | — | US | disclosed |
| US-11584800-B2 | Method of treating cancer comprising administration of anti-HER2 antibody-drug conjugate | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-02-21 | — | — | US | disclosed |
| EP-0441263-A1 | Dye composition for keratinous fibers | KAO CORPORATION (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-5021439-A | Senile dementia and memory dysfunction | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0395244-A1 | Pyridine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1990-10-31 | — | — | EP | disclosed |
| EP-0367393-A2 | New heterocyclic compounds, production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1990-05-09 | — | — | EP | disclosed |
| US-4920103-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0169725-B1 | PROSTAGLANDIN ANALOGUES FOR THE TREATMENT OF BRAIN CELLS ANOXIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-03-21 | — | — | EP | disclosed |
| US-4812475-A | TREATMENT OF OXYGEN DEFICIENCY OF BRAIN | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-03-14 | — | — | US | disclosed |
| EP-0262904-A2 | Modifications of mycinose and 3-0-demethylmycinose in tylosintype macrolides | ELI LILLY AND COMPANY (US) | 1988-04-06 | — | — | EP | disclosed |
| US-4552841-A | N-Acetyl-β-D-glucosaminides for determining N-acetyl-β-D-glucosaminidase activity | SHIONOGI & CO., LTD. (JP) | 1985-11-12 | — | — | US | disclosed |
| US-4433139-A | N-Acetyl-β-D-glucosamnides for determining N-acetyl-β-D-glucosaminidase activity | SHIONOGI & CO., LTD. (JP) | 1984-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190698-A1 | BICYCLIC COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | CYP4A11, PDE3A, GUCY1B1 | ALDH1A1 716/4885LMNA 821/4885HSD17B10 628/4885 |
| US-20240158430-A1 | NOVEL COMPOUND OR SALT THEREOF, AND ANTITUMOR ACTIVATOR CONTAINING SAME AS ACTIVE INGREDIENT | STAT3, STAT6, HDAC1 | ALDH1A1 490/4885LMNA 4364/4885HSD17B10 1785/4885 |
| US-11617733-B2 | Bicyclic compound and use thereof for medical purposes | CYP4A11, PDE3A, GUCY1B1 | ALDH1A1 716/4885LMNA 821/4885HSD17B10 628/4885 |
| US-20050004186-A1 | MEK inhibiting compounds | MAPK1, MAP3K1, MAPK3 | ALDH1A1 1628/4885LMNA 3833/4885HSD17B10 3520/4885 |
| US-11584800-B2 | Method of treating cancer comprising administration of anti-HER2 antibody-drug conjugate | ERBB2, EGFR, H1-2 | ALDH1A1 1073/4885LMNA 160/4885HSD17B10 2952/4885 |
| US-20240083899-A1 | PURINONE DERIVATIVE | BTK, KIT, SYK | ALDH1A1 492/4885LMNA 3626/4885HSD17B10 3011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.