Ethyl Acetate

Ethyl Acetate

SCHEMBL2857167

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nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.64
LMNA P02545 2/20 0.64
HSD17B10 Q99714 2/20 0.64
GAA P10253 2/20 0.54
MGAM O43451 1/20 0.54
SI P14410 1/20 0.54
MGAM2 Q2M2H8 1/20 0.54
CYP4F2 P78329 3/20 0.48
CYP4A11 Q02928 3/20 0.48
CYP1A2 P05177 1/20 0.48
TRPA1 O75762 1/20 0.44
TSHR P16473 3/20 0.41
NR1I2 O75469 1/20 0.39
PGR P06401 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
PTGS2 P35354 1/20 0.39
PDE4D Q08499 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
POLB P06746 2/20 0.38
ALOX15 P16050 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL3310615 1.00 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10GAAMGAM
Ethyl Acetate SCHEMBL16144857 1.00 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10GAAMGAM
Ethyl Acetate SCHEMBL15417972 1.00 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10GAAMGAM
Ethyl Acetate SCHEMBL1259377 1.00 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10GAAMGAM
Ethyl Acetate SCHEMBL14630991 1.00 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10GAAMGAM
Ethyl Acetate SCHEMBL1259419 1.00 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10GAAMGAM
Ethyl Acetate SCHEMBL15418012 1.00 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10GAAMGAM
Ethyl Acetate SCHEMBL1260460 1.00 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10GAAMGAM
Ethyl Acetate SCHEMBL37398 1.00 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10GAAMGAM
Ethyl Acetate SCHEMBL3312144 1.00 ALDH1A1 (0.64) ALDH1A1LMNAHSD17B10GAAMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240083893-A1 COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) 2024-03-14 US disclosed
US-11667628-B2 Compounds for imaging tau proteins that accumulate in brain NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) 2023-06-06 US disclosed
US-20220056020-A1 NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN BRAIN NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) 2022-02-24 US disclosed
US-20200262829-A1 Novel Compounds for Imaging Tau Proteins That Accumulate in the Brain NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECH (JP) 2020-08-20 US disclosed
US-10604516-B2 Compounds for imaging tau proteins that accumulate in the brain NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) 2020-03-31 US disclosed
EP-2767532-B1 NOVEL COMPOUND FOR IMAGING TAU PROTEIN ACCUMULATED IN THE BRAIN NAT INST FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) 2016-07-13 EP disclosed
US-20150239878-A1 Novel Compounds for Imaging Tau Proteins That Accumulate In Brain NATIONAL INSTITUTES FOR QUANTUM AND RADIOLOGICAL SCIENCE AND TECHNOLOGY (JP) 2015-08-27 US disclosed
CN-104736524-A Novel compound for imaging Tau protein accumulated in brain NAT INST RADIOLOG 2015-06-24 CN disclosed
EP-2767532-A1 NOVEL COMPOUND FOR IMAGING TAU PROTEIN ACCUMULATED IN THE BRAIN National Institute of Radiological Sciences (JP) 2014-08-20 EP disclosed
EP-1642880-B1 HSP90 FAMILY PROTEIN INHIBITORS KYOWA HAKKO KIRIN CO LTD (JP) 2013-09-04 EP disclosed
US-7767693-B2 Hsp90 family protein inhibitors KYOWA HAKKO KIRIN CO., LTD. (JP) 2010-08-03 US disclosed
US-20090247522-A1 Hsp90 FAMILY PROTEIN INHIBITORS KYOWA HAKKO KOGYO CO., LTD. (JP) 2009-10-01 US disclosed
US-7538224-B2 Hsp90 family protein inhibitors KYOWA HAKKO KOGYO CO., LTD. (JP) 2009-05-26 US disclosed
US-20070032532-A1 Hsp90 family protein inhibitors KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-02-08 US disclosed
EP-1642880-A1 HSP90 FAMILY PROTEIN INHIBITORS KYOWA HAKKO KOGYO CO., LTD. (JP) 2006-04-05 EP disclosed
US-6569873-B2 Treating or inhibiting metabolic disorders related to insulin resistance or hyperglycemia, atherosclerosis, gastrointestinal disorders, neurogenetic inflammation, glaucoma, ocular hypertension and frequent urination WYETH 2003-05-27 US disclosed
US-20030055079-A1 Azolidines as beta-3 adrenergic receptor agonists WYETH 2003-03-20 US disclosed
US-6465501-B2 USEFUL IN TREATING OR INHIBITING METABOLIC DISORDERS RELATED TO INSULIN RESISTANCE OR HYPERGLYCEMIA, ATHEROSCLEROSIS, GASTROINTESTINAL DISORDERS, NEUROGENETIC INFLAMMATION, GLAUCOMA, OCULAR HYPERTENSION AND INCONTINENCE WYETH 2002-10-15 US disclosed
US-20020032222-A1 Azolidines as beta-3 adrenergic receptor agonists AMERICAN HOME PRODUCTS CORPORATION (US) 2002-03-14 US disclosed
WO-2002006258-A1 AZOLIDINES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS WYETH (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055079-A1 Azolidines as beta-3 adrenergic receptor agonists GPR119, ADRB1, ADRB3 ALDH1A1 1058/4885LMNA 2710/4885HSD17B10 2493/4885
US-20240083893-A1 COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN THE BRAIN MAPT, FABP7, HTT ALDH1A1 1880/4885LMNA 3874/4885HSD17B10 235/4885
US-20070032532-A1 Hsp90 family protein inhibitors HSP90AB1, HSP90B1, HSP90AB2P ALDH1A1 2940/4885LMNA 4283/4885HSD17B10 1023/4885
US-20090247522-A1 Hsp90 FAMILY PROTEIN INHIBITORS HSP90AB1, HSP90B1, HSP90AB2P ALDH1A1 2940/4885LMNA 4283/4885HSD17B10 1023/4885
US-11667628-B2 Compounds for imaging tau proteins that accumulate in brain MAPT, FABP7, HTT ALDH1A1 1691/4885LMNA 3929/4885HSD17B10 218/4885
US-20020032222-A1 Azolidines as beta-3 adrenergic receptor agonists GPR119, ADRB1, ADRB3 ALDH1A1 1058/4885LMNA 2710/4885HSD17B10 2493/4885
US-20200262829-A1 Novel Compounds for Imaging Tau Proteins That Accumulate in the Brain MAPT, FABP7, HTT ALDH1A1 1870/4885LMNA 3862/4885HSD17B10 225/4885
US-20220056020-A1 NOVEL COMPOUNDS FOR IMAGING TAU PROTEINS THAT ACCUMULATE IN BRAIN MAPT, FABP7, HTT ALDH1A1 2088/4885LMNA 3890/4885HSD17B10 246/4885
US-10604516-B2 Compounds for imaging tau proteins that accumulate in the brain MAPT, FABP7, HTT ALDH1A1 1701/4885LMNA 3784/4885HSD17B10 239/4885
US-20150239878-A1 Novel Compounds for Imaging Tau Proteins That Accumulate In Brain MAPT, FABP7, HTT ALDH1A1 1901/4885LMNA 3805/4885HSD17B10 246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.