Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 6/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | FABP2 | P12104 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18978035 | 0.95 | ALDH1A1 (0.48) | LMNAALDH1A1SRD5A2ELANEPPARG | |
| SCHEMBL24108828 | 0.93 | ELANE (0.52) | LMNAELANEPPARGPPARAFABP2 | |
| SCHEMBL18478570 | 0.86 | ACHE (0.42) | LMNAALDH1A1PPARAKMT2AMEN1 | |
| SCHEMBL18885322 | 0.85 | PPARA (0.65) | LMNAALDH1A1SRD5A2ELANEPPARG | |
| SCHEMBL12606795 | 0.84 | NPC1 (0.48) | LMNASRD5A2ELANEPPARGPPARA | |
| SCHEMBL13537025 | 0.84 | ELANE (0.45) | LMNAALDH1A1SRD5A2ELANEPPARG | |
| SCHEMBL13866395 | 0.83 | PPARG (0.48) | LMNAALDH1A1ELANEPPARGPPARA | |
| SCHEMBL17302417 | 0.82 | LMNA (0.61) | LMNAALDH1A1SRD5A2ELANEPPARG | |
| SCHEMBL13969355 | 0.82 | NPC1 (0.62) | LMNAALDH1A1KMT2ANPSR1CYP1A2 | |
| SCHEMBL982170 | 0.81 | CA1 (0.52) | ALDH1A1KMT2AMEN1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140178582-A1 | COMPOSITE MEMBRANE FORMED FROM POLYMER BLEND INCLUDING SELF-ASSEMBLING BLOCK COPOLYMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-06-26 | — | — | US | disclosed |
| US-20110151355-A1 | POLYMER, POLYMER ELECTROLYTE AND USE OF SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-23 | — | — | US | disclosed |