Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023395 | 0.87 | ALDH1A1 (0.44) | ARNOTUMALDH1A1PGRKDM4E | |
| SCHEMBL29033541 | 0.83 | ALDH1A1 (0.47) | NOTUMALDH1A1SRD5A1KDM4EHTT | |
| SCHEMBL17174806 | 0.80 | HDAC1 (0.48) | ARNOTUMALDH1A1PGRSRD5A1 | |
| SCHEMBL14564597 | 0.79 | NOTUM (0.47) | NOTUMALDH1A1SRD5A1KDM4EHTT | |
| SCHEMBL787597 | 0.75 | ALDH1A1 (0.45) | ARNOTUMALDH1A1KDM4EHTT | |
| SCHEMBL8293242 | 0.73 | RARA (0.48) | NOTUMALDH1A1KDM4EHTTF2 | |
| SCHEMBL2616784 | 0.72 | NOTUM (0.58) | NOTUMALDH1A1SRD5A1KDM4EHTT | |
| SCHEMBL29959514 | 0.71 | CYP3A4 (0.50) | ALDH1A1SRD5A1SMN1; SMN2ADRA2ACYP3A4 | |
| SCHEMBL5763435 | 0.71 | CYP3A4 (0.50) | ALDH1A1SRD5A1SMN1; SMN2ADRA2ACYP3A4 | |
| SCHEMBL8130283 | 0.70 | AR (0.43) | ARALDH1A1PGRKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110122475-A1 | PHOTOCHROMIC DICHROIC NAPHTHO-PYRANS AND OPTICAL ARTICLES CONTAINING THEM | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110122475-A1 | PHOTOCHROMIC DICHROIC NAPHTHO-PYRANS AND OPTICAL ARTICLES CONTAINING THEM | NR2E3, NR2C2, NR5A2 | AR 255/4885NOTUM 978/4885ALDH1A1 1244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.