Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763435 | 1.00 | CYP3A4 (0.50) | CYP3A4ALDH1A1ADRA2ASIGMAR1PARP1 | |
| SCHEMBL213183 | 0.88 | SIGMAR1 (0.47) | CYP3A4ALDH1A1ADRA2ASIGMAR1PARP1 | |
| Bromide SCHEMBL4618934 | 0.86 | SIGMAR1 (0.46) | CYP3A4ALDH1A1ADRA2ASIGMAR1PARP1 | |
| Hydrochloric Acid SCHEMBL9190644 | 0.86 | SIGMAR1 (0.48) | CYP3A4ALDH1A1ADRA2ASIGMAR1PARP1 | |
| Phosphine SCHEMBL5925750 | 0.86 | SIGMAR1 (0.46) | CYP3A4ALDH1A1ADRA2ASIGMAR1PARP1 | |
| Ammonia Solution, Strong SCHEMBL8159676 | 0.86 | SIGMAR1 (0.46) | CYP3A4ALDH1A1ADRA2ASIGMAR1PARP1 | |
| Iodide SCHEMBL9192873 | 0.86 | SIGMAR1 (0.46) | CYP3A4ALDH1A1ADRA2ASIGMAR1PARP1 | |
| SCHEMBL9770689 | 0.85 | CYP3A4 (0.41) | CYP3A4ALDH1A1ADRA2ASIGMAR1PARP1 | |
| SCHEMBL30695369 | 0.85 | CYP3A4 (0.41) | CYP3A4ALDH1A1ADRA2ASIGMAR1PARP1 | |
| SCHEMBL29295497 | 0.80 | ALDH1A1 (0.48) | CYP3A4ALDH1A1ADRA2ASIGMAR1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11458083-B2 | Cosmetic and/or dermatological composition containing a merocyanine derivative comprising specific polar groups consisting of hydroxyl- and ether-functionalities | L'OREAL (FR) | 2022-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11458083-B2 | Cosmetic and/or dermatological composition containing a merocyanine derivative comprising specific polar groups consisting of hydroxyl- and ether-functionalities | KRT18, LAGE3, TYR | CYP3A4 931/4885ALDH1A1 1018/4885ADRA2A 3228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.