SCHEMBL12610885

SCHEMBL12610885

CC(C)(C)OC(=O)N1C=C(C(=O)O)C1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.40
ADORA1 P30542 1/20 0.40
NR1H2 P55055 3/20 0.39
GPR119 Q8TDV5 1/20 0.37
USP2 O75604 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ELANE P08246 1/20 0.37
BUB1 O43683 1/20 0.36
MAPK1 P28482 1/20 0.36
KDM4E B2RXH2 1/20 0.36
PKM P14618 1/20 0.36
BCHE P06276 1/20 0.36
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3505154 0.81 ESR2 (0.45) ESR2ADORA1NR1H2GPR119USP2
SCHEMBL17942084 0.75 GPR119 (0.39) ESR2NR1H2GPR119USP2SMN1; SMN2
SCHEMBL19462690 0.74 ADORA1 (0.43) ESR2ADORA1NR1H2GPR119USP2
SCHEMBL28244949 0.74 CTSK (0.38) ESR2NR1H2GPR119ELANEBUB1
SCHEMBL31084282 0.73 ADORA1 (0.33) ESR2ADORA1NR1H2GPR119
SCHEMBL7420791 0.73 ADORA1 (0.36) ESR2ADORA1NR1H2GPR119USP2
SCHEMBL29234093 0.73 ADORA1 (0.42) ESR2ADORA1NR1H2GPR119USP2
SCHEMBL1199488 0.73 GPR119 (0.39) ESR2ADORA1NR1H2GPR119USP2
SCHEMBL28688256 0.72 ESR2 (0.41) ESR2NR1H2GPR119USP2SMN1; SMN2
SCHEMBL28311005 0.72 NR1H2 (0.35) NR1H2GPR119KDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022116-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI-AVENTIS RECHERCHE & DÉVELOPPEMENT (FR) 2026-01-22 US disclosed
EP-4558500-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF Sanofi (FR) 2025-05-28 EP disclosed
WO-2024017977-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI (FR) 2024-01-25 WO disclosed
WO-2012126084-A1 HSP-90 BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND THEIR USE IΝ THE TREATMENT AND PREVENTION OF FUNGAL INFECTIONS PHARMASCIENCE INC. (CA) 2012-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022116-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF MAPK1, MAPK3, MAPK6 ESR2 2465/4885ADORA1 2337/4885NR1H2 866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.