SCHEMBL12620137

SCHEMBL12620137

C[Si]1(C)C=CC2=C1c1ccccc1[Si]2(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RORA P35398 1/20 0.32
RORC P51449 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2174700 0.74 RORA (0.39) RORARORC
SCHEMBL29768232 0.69 RORC (0.50) RORARORC
SCHEMBL1107762 0.69 RORC (0.50) RORARORC
SCHEMBL12408467 0.67 RORA (0.39) RORARORC
SCHEMBL3461769 0.64 ALDH1A1 (0.37) RORARORC
SCHEMBL21454151 0.63 RORA (0.30) RORARORC
SCHEMBL20961741 0.61 CDC25B (0.52) RORARORC
SCHEMBL10356586 0.61
SCHEMBL13451241 0.61 RORC (0.53) RORARORC
SCHEMBL2174022 0.60 RORA (0.33) RORARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7951962-B2 Condensed ring compounds formed by edge sharing between the connecting ring and each of the electron-conjugated aromatic rings, which means bonding between the two atoms; pi-electron conjugated systems; improved solvent solubility allows use in ink jet printing SEIKO EPSON CORPORATION (JP) 2011-05-31 US disclosed
US-20080076935-A1 ORGANIC SEMICONDUCTOR COMPOUND, ORGANIC SEMICONDUCTOR THIN FILM, ORGANIC SEMICONDUCTOR COATING LIQUID, ORGANIC THIN FILM TRANSISTOR, METHODS FOR PRODUCING BIS(BENZO[4,5] THIENO)[2,3-B:3'2'-E][1,4]DITHIIN AND BIS(BENZO [4,5]THIENO)[2,3-B:2'3'-E][1,4]DITHIIN SEIKO EPSON CORPORATION (JP) 2008-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076935-A1 ORGANIC SEMICONDUCTOR COMPOUND, ORGANIC SEMICONDUCTOR THIN FILM, ORGANIC SEMICONDUCTOR COATING LIQUID, ORGANIC THIN FILM TRANSISTOR, METHODS FOR PRODUCING BIS(BENZO[4,5] THIENO)[2,3-B:3'2'-E][1,4]DITHIIN AND BIS(BENZO [4,5]THIENO)[2,3-B:2'3'-E][1,4]DITHIIN ESYT2, DRD4, ESR2 RORA 1302/4885RORC 1118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.