Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.43 |
| ▸ | MEN1 | O00255 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 11/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455608 | 0.85 | KDM4E (0.49) | NPC1MEN1KMT2ACASP3SENP8 | |
| SCHEMBL7465012 | 0.85 | SMPD3 (0.38) | NPC1MEN1KMT2ACASP3SENP8 | |
| Hydrochloric Acid SCHEMBL687553 | 0.83 | KDM4E (0.48) | NPC1MEN1KMT2ACASP3SENP8 | |
| SCHEMBL7460208 | 0.81 | SMPD3 (0.36) | NPC1MEN1KMT2ACASP3SENP8 | |
| SCHEMBL7458579 | 0.79 | KDM5A (0.43) | NPC1MEN1KMT2ACASP3SENP8 | |
| SCHEMBL3833763 | 0.73 | SMPD3 (0.38) | NPC1MEN1KMT2ACASP3SENP8 | |
| SCHEMBL1818323 | 0.73 | RAB9A (0.59) | NPC1MEN1KMT2ARAB9ASMPD3 | |
| Hydrochloric Acid SCHEMBL6382793 | 0.72 | MAPT (0.58) | NPC1MEN1KMT2ARAB9ASMPD3 | |
| Hydrochloric Acid SCHEMBL6620222 | 0.72 | MAPT (0.58) | NPC1MEN1KMT2ARAB9ASMPD3 | |
| SCHEMBL7464311 | 0.70 | SMPD3 (0.36) | NPC1MEN1KMT2ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2213 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443890-B1 | OXIDATION COLOURING AGENT BASED ON BICYCLIC DEVELOPER COMPONENTS | HENKEL AG & CO KGAA (DE) | 2010-01-13 | — | — | EP | claimed |
| EP-1352636-B1 | Oxidation dyeing composition for keratin fibers comprising 2-chloro-6-methyl-3-aminophenol and an oxidation base, and dyeing method | OREAL (FR) | 2009-04-22 | — | — | EP | claimed |
| EP-1413286-B1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | OREAL (FR) | 2009-04-22 | — | — | EP | claimed |
| EP-1405627-B1 | Antipenetrating hair pretreatment composition based on polyethelenoxide polymer(s) and process using said composition for limiting skin penetration by colourants | OREAL (FR) | 2008-04-30 | — | — | EP | claimed |
| WO-2007071686-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| WO-2007071688-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, A PARTICULAR OXIDATION BASE AND A COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| US-7189267-B2 | Oxyethylenated based hair pre-treatment anti-penetration composition and method using such a composition for limiting the penetration of dyes into the skin | L'OREAL (FR) | 2007-03-13 | — | — | US | claimed |
| US-7077871-B2 | Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye | L'OREAL (FR) | 2006-07-18 | — | — | US | claimed |
| EP-1210931-B1 | Keratinic fibres dyeing composition | OREAL (FR) | 2006-04-05 | — | — | EP | claimed |
| EP-1621185-A1 | Hair dyeing composition comprising an elastomeric film-forming polymer and an oxidation dye precursor | L'OREAL (FR) | 2006-02-01 | — | — | EP | claimed |
| EP-0966252-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES COMPRISING 2-CHLORO 6 METHYL 3-AMINOPHENOL AND AN OXIDATION BASE, AND DYEING METHOD | L'OREAL (FR) | 1999-12-29 | — | — | EP | claimed |
| EP-0966951-A1 | Dye composition containing 1,8-bis-(2,5-diaminophenoxy)-3,5-dioxaoctane, an additional oxidation base and a coupler, and dyeing process | L'OREAL (FR) | 1999-12-29 | — | — | EP | claimed |
| WO-1999066891-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 1999-12-29 | — | — | WO | claimed |
| WO-1999066892-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 1999-12-29 | — | — | WO | claimed |
| WO-1999048465-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES CONTAINING A 3-AMINOPYRIDINE AZO DERIVATIVE AND DYEING METHOD USING SAID COMPOSITION | L'OREAL (FR) | 1999-09-30 | — | — | WO | claimed |
| WO-1999036039-A1 | KERATINOUS FIBRE OXIDATION DYEING COMPOSITION CONTAINING A LACCASE AND DYEING METHOD USING SAME | L'OREAL (FR) | 1999-07-22 | — | — | WO | claimed |
| WO-1999011230-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES COMPRISING 2-CHLORO 6 METHYL 3-AMINOPHENOL AND AN OXIDATION BASE, AND DYEING METHOD | L'OREAL (FR) | 1999-03-11 | — | — | WO | claimed |
| WO-1998055083-A1 | KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME | L'OREAL (FR) | 1998-12-10 | — | — | WO | claimed |
| EP-0847271-A1 | PYRAZOLO-(1,5-a)-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND HAIR DYES CONTAINING THESE | L'OREAL (FR) | 1998-06-17 | — | — | EP | claimed |
| WO-1997049378-A1 | PYRAZOLO-(1,5-a)-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND HAIR DYES CONTAINING THESE | L'OREAL (FR) | 1997-12-31 | — | — | WO | claimed |