Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | NPC1 | O15118 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6620222 | 0.98 | MAPT (0.58) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6382793 | 0.98 | MAPT (0.58) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL7460087 | 0.85 | KDM4E (0.57) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL7466198 | 0.82 | RAB9A (0.43) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL5317916 | 0.81 | KDM4E (0.42) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL31465402 | 0.81 | MAPT (0.61) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8156856 | 0.80 | KDM4E (0.41) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL23181411 | 0.79 | RAB9A (0.54) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL24225890 | 0.78 | KDM4E (0.59) | RAB9AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL7455608 | 0.73 | KDM4E (0.49) | RAB9AKDM4EMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635091-B2 | Oxidation color dye and coupler | L'OREAL S. A. (FR) | 2003-10-21 | — | — | US | claimed |
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | L'OREAL SA (FR) | 2002-12-05 | — | — | US | claimed |
| US-20020032934-A1 | Composition for oxidation dyeing of keratin fibers, comprising at least one oxidation base chosen from 5-methylpyrazolo(1,5-a)pyrimidine-3,7-diamine and addition salts thereof; dyeing processes using them | L'OREAL S.A. (FR) | 2002-03-21 | — | — | US | claimed |
| EP-1175198-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2002-01-30 | — | — | EP | claimed |
| EP-1155680-A1 | Oxidation dyeing compositions for keratinous fibres comprising at least 5-methylpyrazolo(1,5-a)pyrimidine-3,7-diamine as oxidation base ; dyeing method of use therof | L'OREAL (FR) | 2001-11-21 | — | — | EP | claimed |
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | claimed |
| WO-2001062220-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2001-08-30 | — | — | WO | claimed |
| EP-2352483-A1 | HAIR COLOURING METHOD COMPRISING AFTERTREATMENT | Henkel AG & Co. KGaA (DE) | 2011-08-10 | — | — | EP | disclosed |
| EP-2315576-A1 | CATIONIC ACETYLPYRIDINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | Henkel AG & Co. KGaA (DE) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010060730-A1 | HAIR COLOURING METHOD COMPRISING AFTERTREATMENT | HENKEL AG & CO. KGAA (DE) | 2010-06-03 | — | — | WO | disclosed |
| WO-2010022996-A1 | CATIONIC ACETYLPYRIDINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2010-03-04 | — | — | WO | disclosed |
| EP-1129689-B1 | Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing | OREAL (FR) | 2008-07-09 | — | — | EP | disclosed |
| EP-1457199-B1 | Coupling agents having a 2,3,5-triaminopyridine structure and their use for dyeing keratinic fibres | OREAL (FR) | 2008-05-14 | — | — | EP | disclosed |
| EP-1175198-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2002-01-30 | — | — | EP | disclosed |
| EP-1155680-A1 | Oxidation dyeing compositions for keratinous fibres comprising at least 5-methylpyrazolo(1,5-a)pyrimidine-3,7-diamine as oxidation base ; dyeing method of use therof | L'OREAL (FR) | 2001-11-21 | — | — | EP | disclosed |
| EP-1155680-A1 | Oxidation dyeing compositions for keratinous fibres comprising at least 5-methylpyrazolo(1,5-a)pyrimidine-3,7-diamine as oxidation base ; dyeing method of use therof | L'OREAL (FR) | 2001-11-21 | — | — | EP | disclosed |
| EP-1155680-A1 | Oxidation dyeing compositions for keratinous fibres comprising at least 5-methylpyrazolo(1,5-a)pyrimidine-3,7-diamine as oxidation base ; dyeing method of use therof | L'OREAL (FR) | 2001-11-21 | — | — | EP | disclosed |
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | disclosed |
| EP-1129689-A2 | Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing | L'OREAL (FR) | 2001-09-05 | — | — | EP | disclosed |
| WO-2001062220-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2001-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | KRT18, FH, FGB | RAB9A 4478/4885KDM4E 868/4885MAPT 563/4885 |
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | FH, KRT18, CYB5R3 | RAB9A 4737/4885KDM4E 1443/4885MAPT 879/4885 |
| US-20020032934-A1 | Composition for oxidation dyeing of keratin fibers, comprising at least one oxidation base chosen from 5-methylpyrazolo(1,5-a)pyrimidine-3,7-diamine and addition salts thereof; dyeing processes using them | KRT18, UNG, DPYD | RAB9A 4731/4885KDM4E 259/4885MAPT 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.