Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465012 | 0.85 | SMPD3 (0.38) | SMPD3KDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL7455608 | 0.85 | KDM4E (0.49) | SMPD3KDM4EALDH1A1PKMHSD17B10 | |
| Hydrochloric Acid SCHEMBL687553 | 0.83 | KDM4E (0.48) | SMPD3KDM4EALDH1A1PKMHSD17B10 | |
| SCHEMBL7464311 | 0.81 | SMPD3 (0.36) | SMPD3KDM4EALDH1A1PKMHSD17B10 | |
| SCHEMBL7465595 | 0.79 | KDM5A (0.38) | SMPD3MEN1NPC1KMT2ARAB9A | |
| SCHEMBL126254 | 0.73 | NPC1 (0.43) | SMPD3KDM4EALDH1A1PKMHSD17B10 | |
| SCHEMBL7460208 | 0.70 | SMPD3 (0.36) | SMPD3KDM4EALDH1A1MEN1NPC1 | |
| SCHEMBL7460087 | 0.69 | KDM4E (0.57) | KDM4EALDH1A1PKMHSD17B10MEN1 | |
| SCHEMBL1818323 | 0.69 | RAB9A (0.59) | SMPD3KDM4EALDH1A1PKMHSD17B10 | |
| SCHEMBL7458579 | 0.68 | KDM5A (0.43) | SMPD3KDM4EALDH1A1PKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | L'OREAL SA (FR) | 2002-12-05 | — | — | US | claimed |
| EP-1175198-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2002-01-30 | — | — | EP | claimed |
| WO-2001062220-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2001-08-30 | — | — | WO | claimed |
| EP-3474815-A1 | PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION | L'OREAL (FR) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017220676-A1 | PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION | L'OREAL (FR) | 2017-12-28 | — | — | WO | disclosed |
| EP-1762223-B1 | Composition for dyeing keratin fibres comprising at least one oxidation base and a particular polyoxyethylenated sorbitan ester | ORÉAL L (FR) | 2016-04-13 | — | — | EP | disclosed |
| EP-2065073-B1 | Composition for the oxidation dyeing of keratin fibres comprising a cellulose with hydrophobic substituents, an oxidation dye and a long-chain fatty alcohol | ORÉAL L (FR) | 2015-08-19 | — | — | EP | disclosed |
| EP-2065074-B1 | Composition for the oxidation dyeing of keratin fibres comprising a cellulose with hydrophobic substituent(s), an oxidation dye and a cationic polymer | ORÉAL L (FR) | 2014-06-18 | — | — | EP | disclosed |
| EP-1762222-B2 | Process for colouring keratin fibres comprising a step of treating the scalp with a particular sorbitan ester | OREAL (FR) | 2013-08-21 | — | — | EP | disclosed |
| EP-1762222-B1 | Process for colouring keratin fibres comprising a step of treating the scalp with a particular sorbitan ester | OREAL (FR) | 2009-10-07 | — | — | EP | disclosed |
| EP-2065073-A2 | Composition for the oxidation dyeing of keratin fibres comprising a cellulose with hydrophobic substituents, an oxidation dye and a long-chain fatty alcohol | L'Oréal (FR) | 2009-06-03 | — | — | EP | disclosed |
| EP-2065074-A2 | Composition for the oxidation dyeing of keratin fibres comprising a cellulose with hydrophobic substituent(s), an oxidation dye and a cationic polymer | L'Oréal (FR) | 2009-06-03 | — | — | EP | disclosed |
| EP-1879547-A1 | DYEING COMPOSITION COMPRISING A DYE AND A PROPYLENE GLYCOL DERIVATIVE | L'Oréal (FR) | 2008-01-23 | — | — | EP | disclosed |
| EP-1762223-A1 | Composition for dyeing keratin fibres comprising at least one oxidation base and a particular polyoxyethylenated sorbitan ester | L'Oréal (FR) | 2007-03-14 | — | — | EP | disclosed |
| EP-1762222-A1 | Process for colouring keratin fibres comprising a step of treating the scalp with a particular sorbitan ester | L'Oréal (FR) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006114529-A1 | DYEING COMPOSITION COMPRISING A DYE AND A PROPYLENE GLYCOL DERIVATIVE | L'OREAL (FR) | 2006-11-02 | — | — | WO | disclosed |
| EP-1585488-A1 | NOVEL PHENYLENEDIAMINE DERIVATIVE COUPLING CONSTITUENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004058206-A1 | NOVEL PHENYLENEDIAMINE DERIVATIVE COUPLING CONSTITUENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | disclosed |
| US-20040122782-A1 | Process for determining the composition of a dye product | L'OREAL (FR) | 2004-06-24 | — | — | US | disclosed |
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | L'OREAL SA (FR) | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | FH, KRT18, CYB5R3 | SMPD3 4708/4885KDM4E 1443/4885ALDH1A1 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.