Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12762351 | 0.92 | SLC1A3 (0.52) | ALDH1A1SLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL12629279 | 0.92 | SLC1A3 (0.52) | ALDH1A1SLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL12629282 | 0.91 | ALDH1A1 (0.46) | ALDH1A1SLC1A3SLC1A2SLC1A1GRM8 | |
| SCHEMBL22121087 | 0.85 | SLC7A5 (0.51) | ALDH1A1TDP1ATMGRM8GRM6 | |
| SCHEMBL12629318 | 0.82 | SLC1A3 (0.52) | ALDH1A1SLC1A3SLC1A2SLC1A1GRM8 | |
| SCHEMBL1117276 | 0.82 | SLC1A3 (0.52) | ALDH1A1SLC1A3SLC1A2SLC1A1GRM8 | |
| SCHEMBL13464176 | 0.81 | SLC1A1 (0.54) | SLC1A3SLC1A2SLC1A1TDP1KDM4E | |
| SCHEMBL13620595 | 0.79 | SLC1A1 (0.49) | SLC1A3SLC1A2SLC1A1TDP1KDM4E | |
| SCHEMBL10914789 | 0.78 | ATM (0.50) | ALDH1A1TDP1ATMRECQL | |
| SCHEMBL10914791 | 0.78 | ATM (0.50) | ALDH1A1TDP1ATMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110104057-A1 | Novel [F-18]-labelled L-glutamic acid and L-glutamine derivatives (II), their use and processes for their preparation | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110104057-A1 | Novel [F-18]-labelled L-glutamic acid and L-glutamine derivatives (II), their use and processes for their preparation | GLUL, QPCT, SLC1A2 | ALDH1A1 1298/4885SLC1A3 9/4885SLC1A2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.