Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 3/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12762351 | 0.89 | SLC1A3 (0.52) | SLC1A1SLC1A3SLC1A2GRM2GRM3 | |
| SCHEMBL12629279 | 0.89 | SLC1A3 (0.52) | SLC1A1SLC1A3SLC1A2GRM2GRM3 | |
| SCHEMBL13620595 | 0.85 | SLC1A1 (0.49) | SLC1A1SLC1A3SLC1A2GRM2GRM3 | |
| SCHEMBL13464177 | 0.81 | SLC1A1 (0.59) | SLC1A1SLC1A3SLC1A2GRM2GRM3 | |
| SCHEMBL12629318 | 0.81 | SLC1A3 (0.52) | SLC1A1SLC1A3SLC1A2RECQLGRIK1 | |
| SCHEMBL1117276 | 0.81 | SLC1A3 (0.52) | SLC1A1SLC1A3SLC1A2RECQLGRIK1 | |
| SCHEMBL12629319 | 0.81 | ALDH1A1 (0.43) | SLC1A1SLC1A3SLC1A2KDM4EUSP2 | |
| SCHEMBL15947420 | 0.80 | SLC1A1 (0.57) | SLC1A1SLC1A3SLC1A2GRM2GRM3 | |
| SCHEMBL13623320 | 0.77 | SLC1A1 (0.57) | SLC1A1SLC1A3SLC1A2GRM2GRM3 | |
| SCHEMBL12762356 | 0.77 | SLC1A2 (0.54) | SLC1A1SLC1A3SLC1A2GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141090-A9 | {F-19} -LABELED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVE (III), USE THEREOF AND METHOD FOR OBTAINING THEM | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-03-25 | — | — | WO | disclosed |
| WO-2009141090-A1 | {F-19} -LABELED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVE (III), USE THEREOF AND METHOD FOR OBTAINING THEM | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009141079-A1 | NOVEL [F-18]-LABELLED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVES (II), USE THEREOF AND METHOD FOR THEIR PRODUCTION | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-11-26 | — | — | WO | disclosed |