⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17201490 | 0.84 | LMNA (0.36) | — | |
| SCHEMBL27852188 | 0.84 | LMNA (0.36) | — | |
| SCHEMBL32659786 | 0.78 | LMNA (0.35) | — | |
| SCHEMBL3720998 | 0.78 | — | — | |
| SCHEMBL4651593 | 0.76 | — | — | |
| SCHEMBL183974 | 0.74 | — | — | |
| SCHEMBL107295 | 0.74 | — | — | |
| SCHEMBL818248 | 0.74 | — | — | |
| SCHEMBL19363012 | 0.74 | — | — | |
| SCHEMBL3927878 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404870-B2 | ((2S,4R)-4,6-dihydroxytetrahydro-2H-pyran-2-yl)methyl carboxylate and process for the production thereof | LEK PHARMACEUTICALS D.D. (SI) | 2013-03-26 | — | — | US | disclosed |
| US-20110046375-A1 | ((2S,4R)-4,6-DIHYDROXYTETRAHYDRO-2H-PYRAN-2-YL)METHYL CARBOXYLATE AND PROCESS FOR THE PRODUCTION THEREOF | LEK PHARMACEUTICALS D.D. (SI) | 2011-02-24 | — | — | US | disclosed |
| EP-2247739-A2 | ((2S,4R)-4,6-DIHYDROXYTETRAHYDRO-2H-PYRAN-2-YL) METHYL CARBOXYLATE AND PROCESS FOR ITS PRODUCTION EMPLOYING A 2-DEOXYRIBOSE-5-PHOSPHATE ALDOLASE | LEK Pharmaceuticals d.d. (SI) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009092702-A2 | ((2S,4R)-4,6-DIHYDROXYTETRAHYDRO-2H-PYRAN-2-YL)METHYL CARBOXYLATE AND PROCESS FOR THE PRODUCTION THEREOF | LEK PHARMACEUTICALS D.D. (SI) | 2009-07-30 | — | — | WO | disclosed |