Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27852188 | 1.00 | LMNA (0.36) | LMNAGBA1 | |
| SCHEMBL1262952 | 0.84 | — | — | |
| SCHEMBL15858 | 0.79 | LMNA (0.40) | LMNAGBA1 | |
| SCHEMBL3803965 | 0.79 | LMNA (0.40) | LMNAGBA1 | |
| SCHEMBL6669482 | 0.79 | LMNA (0.40) | LMNAGBA1 | |
| SCHEMBL592850 | 0.79 | LMNA (0.40) | LMNAGBA1 | |
| SCHEMBL15630 | 0.79 | LMNA (0.40) | LMNAGBA1 | |
| SCHEMBL2243421 | 0.77 | LMNA (0.39) | LMNAGBA1 | |
| SCHEMBL443462 | 0.77 | LMNA (0.39) | LMNAGBA1 | |
| SCHEMBL11441770 | 0.77 | LMNA (0.39) | LMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746336-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-09-05 | — | — | US | disclosed |
| US-20190345462-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | UNITED STATES DEPARTMENT OF ENERGY | 2019-11-14 | — | — | US | disclosed |
| US-10233431-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-03-19 | — | — | US | disclosed |
| US-20150307855-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190345462-A1 | Producing 3-Hydroxycarboxylic Acid and Ketone Using Polyketide Synthases | COASY, FASN, DHPS | LMNA 2551/4885GBA1 2471/4885 |
| US-11746336-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | COASY, FASN, DHPS | LMNA 2551/4885GBA1 2471/4885 |
| US-10233431-B2 | Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases | COASY, FASN, DHPS | LMNA 2551/4885GBA1 2471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.