Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 known ✓ | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 known ✓ | P43681 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.40 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27752712 | 0.99 | CYP1A2 (0.43) | CYP1A2CYP2C9CHRM1CHRM3CHRM5 | |
| SCHEMBL16592456 | 0.92 | CYP1A2 (0.43) | CYP1A2CYP2C9CHRM1CHRM3CHRM5 | |
| SCHEMBL11794391 | 0.90 | CA1 (0.46) | CYP1A2CYP2C9SMN1; SMN2CA1CA2 | |
| SCHEMBL895605 | 0.90 | CHRM1 (0.40) | CYP1A2CYP2C9CHRM1CHRM3CHRM5 | |
| SCHEMBL1262969 | 0.89 | CHRM1 (0.42) | CHRM1CHRM3CHRM5CHRM2CHRM4 | |
| Trimethylammonium SCHEMBL28404363 | 0.87 | CYP1A2 (0.38) | CYP1A2CYP2C9SMN1; SMN2CA1CA2 | |
| Acetylcholine SCHEMBL14840381 | 0.86 | CHRM1 (0.58) | CYP1A2CYP2C9CHRM1CHRM3CHRM5 | |
| Acetylcholine SCHEMBL28024294 | 0.85 | CHRM1 (0.56) | CYP1A2CYP2C9CHRM1CHRM3CHRM5 | |
| Trimethylammonium SCHEMBL28403993 | 0.83 | LMNA (0.39) | CYP1A2CYP2C9SMN1; SMN2CA1CA2 | |
| SCHEMBL14691490 | 0.83 | CYP1A2 (0.45) | CYP1A2CYP2C9SMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968083-B2 | Methods of manufacturing deodorants, and deodorants resulting thereof | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2011-06-28 | — | — | US | claimed |
| US-20050232880-A1 | Methods of manufacturing deodorants, and deodorants resulting thereof | HONG KONG POLYTECHNIC UNIVERSITY, THE (CN) | 2005-10-20 | — | — | US | claimed |
| US-6001549-A | IMAGING ELEMENT CONTAINING ANTISTATIC AGENT | EASTMAN KODAK COMPANY (US) | 1999-12-14 | — | — | US | claimed |
| US-7968083-B2 | Methods of manufacturing deodorants, and deodorants resulting thereof | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2011-06-28 | — | — | US | disclosed |
| US-7896485-B2 | Light cure of cationic ink on acidic substrates | GERBER SCIENTIFIC INTERNATIONAL, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7878644-B2 | Light cure of cationic ink on acidic substrates | GERBER SCIENTIFIC INTERNATIONAL, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| EP-1604825-B1 | Ink jet recording method | FUJIFILM CORP (JP) | 2010-09-22 | — | — | EP | disclosed |
| US-20100168282-A1 | DISPERSION COMPRISING INORGANIC PARTICLES, WATER, AND AT LEAST ONE POLYMERIC ADDITIVE | EVONIK ROEHM GMBH (DE) | 2010-07-01 | — | — | US | disclosed |
| EP-1674536-B1 | Inkjet ink composition | FUJIFILM CORP (JP) | 2009-10-21 | — | — | EP | disclosed |
| US-7441883-B2 | Production process of inkjet ink composition and inkjet composition | FUJIFILM CORPORATION (JP) | 2008-10-28 | — | — | US | disclosed |
| EP-1512730-B1 | Ink composition and inkjet recording method | FUJIFILM CORP (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-0201186-B1 | METHOD OF TREATING PHOTOGRAPHIC WASTE SOLUTIONS AND AUTOMATIC PHOTOGRAPH PROCESSOR | KONICA CORPORATION (JP) | 1990-05-30 | — | — | EP | disclosed |
| EP-0201186-A1 | Method of treating photographic waste solutions and automatic photograph processor | KONICA CORPORATION (JP) | 1986-11-12 | — | — | EP | disclosed |
| EP-0042307-B1 | AN OPTICAL RECORDING ELEMENT AND A METHOD OF RECORDING INFORMATION USING THE ELEMENT | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-09-10 | — | — | EP | disclosed |
| US-4340655-A | Thermal and mechanical barrier layers for optical recording elements | EASTMAN KODAK COMPANY (US) | 1982-07-20 | — | — | US | disclosed |
| EP-0042307-A2 | An optical recording element and a method of recording information using the element | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1981-12-23 | — | — | EP | disclosed |
| US-4166093-A | REDUCTION OF DETECTABLE SPECIES MIGRATION IN ELEMENTS FOR THE ANALYSIS OF LIQUIDS | EASTMAN KODAK COMPANY (US) | 1979-08-28 | — | — | US | disclosed |
| EP-0000247-A1 | Water-absorbent starch copolymerisates and method for their preparation. | A.E. STALEY MANUFACTURING COMPANY (US) | 1979-01-10 | — | — | EP | disclosed |
| US-4133687-A | Photographic elements having hydrophilic colloid layers containing compounds having activator precursors and hydrophobic developing agents uniformly loaded in latex polymer particles | EASTMAN KODAK COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4115332-A | Water-absorbent starch copolymerizates | A. E. STALEY MANUFACTURING COMPANY (US) | 1978-09-19 | — | — | US | disclosed |