Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 16/20 | 0.76 |
| ▸ | MMP10 | P09238 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12629881 | 0.89 | DUT (0.60) | DUTCA12CA1CA2CA9 | |
| SCHEMBL12629734 | 0.88 | DUT (0.75) | DUTCA12CA1CA2CA9 | |
| SCHEMBL12629736 | 0.84 | DUT (0.75) | DUTMMP10MMP13CA12CA1 | |
| SCHEMBL12630248 | 0.80 | DUT (0.76) | DUTMMP10MMP13LMNA | |
| SCHEMBL20351363 | 0.79 | DUT (0.68) | DUT | |
| SCHEMBL12630519 | 0.79 | DUT (0.66) | DUTLMNA | |
| SCHEMBL18379760 | 0.78 | DUT (0.66) | DUT | |
| SCHEMBL12629878 | 0.77 | DUT (0.77) | DUTCA12CA1CA2CA9 | |
| SCHEMBL20351362 | 0.77 | DUT (0.64) | DUT | |
| SCHEMBL12629880 | 0.75 | DUT (0.60) | DUTCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011065545-A1 | 5-FLUOROURACIL COMPOUND HAVING dUTPase-INHIBITING ACTIVITY OR SALT THEREOF | 大鵬薬品工業株式会社 (JP) | 2011-06-03 | — | — | WO | disclosed |