Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 18/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP10 | P09238 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12629740 | 0.84 | DUT (0.75) | DUTMMP10MMP13 | |
| SCHEMBL12629875 | 0.82 | DUT (0.75) | DUT | |
| SCHEMBL12629741 | 0.80 | DUT (0.76) | DUTLMNAMMP10MMP13 | |
| SCHEMBL12630541 | 0.79 | DUT (0.77) | DUT | |
| SCHEMBL12629735 | 0.79 | DUT (0.67) | DUT | |
| SCHEMBL12630219 | 0.79 | DUT (0.66) | DUTLMNA | |
| SCHEMBL12629717 | 0.77 | DUT (0.67) | DUTMMP10MMP13 | |
| SCHEMBL12629881 | 0.70 | DUT (0.60) | DUTLMNA | |
| SCHEMBL12629869 | 0.69 | DUT (0.74) | DUT | |
| SCHEMBL1606944 | 0.69 | DUT (1.00) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011065545-A1 | 5-FLUOROURACIL COMPOUND HAVING dUTPase-INHIBITING ACTIVITY OR SALT THEREOF | 大鵬薬品工業株式会社 (JP) | 2011-06-03 | — | — | WO | disclosed |