Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 18/20 | 0.77 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12629734 | 0.89 | DUT (0.75) | DUTCA12CA1CA2CA9 | |
| SCHEMBL12629880 | 0.89 | DUT (0.60) | DUTCA12CA1CA2CA9 | |
| SCHEMBL12629881 | 0.88 | DUT (0.60) | DUTCA12CA1CA2CA9 | |
| SCHEMBL1409524 | 0.87 | DUT (1.00) | DUT | |
| SCHEMBL21536721 | 0.81 | DUT (0.71) | DUT | |
| SCHEMBL1409688 | 0.80 | DUT (0.69) | DUT | |
| SCHEMBL12696987 | 0.80 | DUT (0.69) | DUT | |
| SCHEMBL27806918 | 0.79 | DUT (0.67) | DUT | |
| SCHEMBL12629731 | 0.78 | DUT (0.77) | DUT | |
| SCHEMBL12629741 | 0.77 | DUT (0.76) | DUTCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011065545-A1 | 5-FLUOROURACIL COMPOUND HAVING dUTPase-INHIBITING ACTIVITY OR SALT THEREOF | 大鵬薬品工業株式会社 (JP) | 2011-06-03 | — | — | WO | disclosed |