Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 12/20 | 0.69 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1409688 | 0.90 | DUT (0.69) | DUTNAMPTACACAKAT6AHTR1A | |
| SCHEMBL27806918 | 0.89 | DUT (0.67) | DUTNAMPTACACAKAT6AHTR1A | |
| SCHEMBL21536721 | 0.83 | DUT (0.71) | DUTNAMPT | |
| SCHEMBL1409524 | 0.82 | DUT (1.00) | DUT | |
| SCHEMBL12629878 | 0.80 | DUT (0.77) | DUT | |
| SCHEMBL1409352 | 0.80 | DUT (0.67) | DUTNAMPTKAT6AHTR1AHTR7 | |
| SCHEMBL27827503 | 0.78 | DUT (0.65) | DUTNAMPTKAT6A | |
| SCHEMBL12630200 | 0.76 | DUT (0.56) | DUTKAT6A | |
| SCHEMBL21536674 | 0.75 | DUT (0.60) | DUTNAMPT | |
| SCHEMBL12630857 | 0.74 | DUT (0.55) | DUTKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295414-B1 | URACIL COMPOUND HAVING INHIBITORY ACTIVITY ON HUMAN DEOXYURIDINE TRIPHOSPHATASE OR SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2012-09-26 | — | — | EP | disclosed |