Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 11/20 | 0.56 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1409688 | 0.86 | DUT (0.69) | DUTKAT6A | |
| SCHEMBL12629721 | 0.85 | DUT (0.67) | DUTKAT6AGRM2 | |
| SCHEMBL12630857 | 0.82 | DUT (0.55) | DUTKAT6A | |
| SCHEMBL12629880 | 0.81 | DUT (0.60) | DUT | |
| SCHEMBL27806918 | 0.79 | DUT (0.67) | DUTKAT6A | |
| SCHEMBL12696987 | 0.76 | DUT (0.69) | DUTKAT6A | |
| SCHEMBL20189654 | 0.72 | DUT (0.70) | DUTKAT6AGRM2 | |
| SCHEMBL1409352 | 0.71 | DUT (0.67) | DUTKAT6A | |
| SCHEMBL18379994 | 0.71 | DUT (0.68) | DUTKAT6AGRM2 | |
| SCHEMBL20374165 | 0.70 | DUT (0.67) | DUTKAT6AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011065545-A1 | 5-FLUOROURACIL COMPOUND HAVING dUTPase-INHIBITING ACTIVITY OR SALT THEREOF | 大鵬薬品工業株式会社 (JP) | 2011-06-03 | — | — | WO | disclosed |