SCHEMBL12630857 — predicted protein targets

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	DUT	P33316	10/20	0.55

▸	FBP1	P09467	1/20	0.34

▸	LMNA	P02545	2/20	0.34

▸	RORA	P35398	1/20	0.34

▸	RORC	P51449	1/20	0.34

▸	NR1H2	P55055	1/20	0.34

▸	ALPL	P05186	1/20	0.34

▸	ALDH1A1	P00352	1/20	0.34

▸	POLB	P06746	1/20	0.34

▸	KDM4E	B2RXH2	1/20	0.33

▸	MEN1	O00255	1/20	0.33

▸	NPC1	O15118	1/20	0.33

▸	MAPT	P10636	1/20	0.33

▸	HPGD	P15428	1/20	0.33

▸	RAB9A	P51151	1/20	0.33

▸	KMT2A	Q03164	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	HCRTR1	O43613	1/20	0.33

▸	HCRTR2	O43614	1/20	0.33

▸	BACE1	P56817	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12630519	0.85	DUT (0.66)	DUTLMNARORARORCNR1H2
SCHEMBL1409688	0.84	DUT (0.69)	DUTKAT6A
SCHEMBL12630200	0.82	DUT (0.56)	DUTKAT6A
SCHEMBL12629881	0.80	DUT (0.60)	DUTLMNA
SCHEMBL27806918	0.77	DUT (0.67)	DUTKAT6A
SCHEMBL12696987	0.74	DUT (0.69)	DUTKAT6A
SCHEMBL26022939	0.71	DUT (0.50)	DUT
SCHEMBL20351363	0.71	DUT (0.68)	DUT
SCHEMBL1409436	0.71	DUT (0.63)	DUTLMNARORARORCNR1H2
SCHEMBL18379760	0.70	DUT (0.66)	DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011065545-A1	5-FLUOROURACIL COMPOUND HAVING dUTPase-INHIBITING ACTIVITY OR SALT THEREOF	大鵬薬品工業株式会社 (JP)	2011-06-03	—	—	WO	disclosed