Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 3/20 | 0.35 |
| ▸ | QDPR | P09417 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12529424 | 0.82 | HDAC6 (0.43) | KIF11MAPTLMNANOTUMSMN1; SMN2 | |
| SCHEMBL12529444 | 0.80 | DYRK1A (0.62) | KIF11DYRK1ADYRK1BCYP11B1CYP11B2 | |
| SCHEMBL14817169 | 0.80 | TSHR (0.38) | KIF11MAPTLMNANOTUMSMN1; SMN2 | |
| SCHEMBL18858485 | 0.78 | ALAD (0.47) | KIF11MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL12529448 | 0.78 | ALAD (0.47) | MAPTNPC1RAB9AAKT1CYP1A2 | |
| SCHEMBL26781848 | 0.78 | CYP2A6 (0.36) | DYRK1ADYRK1B | |
| SCHEMBL26781853 | 0.75 | HSD17B1 (0.41) | KIF11TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL668112 | 0.75 | MAPK14 (0.50) | CYP3A4 | |
| SCHEMBL24037300 | 0.74 | HRH4 (0.36) | KIF11 | |
| SCHEMBL24037301 | 0.74 | COMT (0.36) | KIF11MAPTSMN1; SMN2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947684-B2 | anticoagulants; immunomoderators; antiinflammatory agents | AVENTIS PHARMACEUTICALS INC. (US) | 2011-05-24 | — | — | US | disclosed |