Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2031324 | 1.00 | ALDH1A1 (0.49) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12631366 | 0.90 | ALDH1A1 (0.57) | ALDH1A1RAB9AKMT2ALMNAAPP | |
| SCHEMBL2033680 | 0.90 | ALDH1A1 (0.57) | ALDH1A1RAB9AKMT2ALMNAAPP | |
| SCHEMBL12631614 | 0.89 | ALDH1A1 (0.46) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL2030221 | 0.88 | ALDH1A1 (0.48) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12632587 | 0.88 | ALDH1A1 (0.48) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL2036513 | 0.88 | ALDH1A1 (0.55) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12632360 | 0.86 | ALDH1A1 (0.50) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12632364 | 0.85 | KMT2A (0.49) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12632586 | 0.85 | APP (0.46) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073277-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | disclosed |