Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030221 | 1.00 | ALDH1A1 (0.48) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL2031324 | 0.88 | ALDH1A1 (0.49) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12632585 | 0.88 | ALDH1A1 (0.49) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL2036513 | 0.87 | ALDH1A1 (0.55) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12631366 | 0.87 | ALDH1A1 (0.57) | ALDH1A1RAB9AKMT2ALMNAGAA | |
| SCHEMBL2033680 | 0.87 | ALDH1A1 (0.57) | ALDH1A1RAB9AKMT2ALMNAGAA | |
| SCHEMBL12631614 | 0.86 | ALDH1A1 (0.46) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12632586 | 0.84 | APP (0.46) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL2035987 | 0.84 | APP (0.46) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 | |
| SCHEMBL12632588 | 0.84 | ALDH1A1 (0.51) | ALDH1A1RAB9AKMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073277-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | disclosed |