Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12631366 | 1.00 | ALDH1A1 (0.57) | ALDH1A1GAALMNATSHRNPC1 | |
| SCHEMBL12631602 | 0.90 | KMT2A (0.60) | ALDH1A1GAALMNATSHRNPC1 | |
| SCHEMBL2010049 | 0.90 | KMT2A (0.60) | ALDH1A1GAALMNATSHRNPC1 | |
| SCHEMBL2031324 | 0.90 | ALDH1A1 (0.49) | ALDH1A1GAALMNATSHRNPC1 | |
| SCHEMBL12632585 | 0.90 | ALDH1A1 (0.49) | ALDH1A1GAALMNATSHRNPC1 | |
| SCHEMBL2035987 | 0.89 | APP (0.46) | ALDH1A1GAALMNAKMT2AAPP | |
| SCHEMBL12632586 | 0.89 | APP (0.46) | ALDH1A1GAALMNAKMT2AAPP | |
| SCHEMBL12631678 | 0.87 | ALDH1A1 (0.46) | ALDH1A1GAALMNATSHRNPC1 | |
| SCHEMBL12631614 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2ARAB9A | |
| SCHEMBL12632371 | 0.87 | ALDH1A1 (0.46) | ALDH1A1GAALMNATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073277-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS Kv1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |