Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | AGXT | P21549 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | LGMN | Q99538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39888 | 0.89 | LMNA (0.52) | RAB9AAGXTNCF1ALDH1A1HTT | |
| SCHEMBL12635598 | 0.86 | ST14 (0.55) | ST14RAB9AAGXTALDH1A1HTT | |
| SCHEMBL2351767 | 0.83 | AGXT (0.46) | RAB9AAGXTNCF1ALDH1A1HTT | |
| SCHEMBL12635595 | 0.82 | ALDH1A1 (0.51) | ST14AGXTNCF1ALDH1A1MAPT | |
| SCHEMBL30440657 | 0.79 | LTA4H (0.66) | RAB9AALDH1A1HTTMAPTNPC1 | |
| SCHEMBL1239752 | 0.79 | MAPT (0.55) | RAB9AAGXTNCF1ALDH1A1HTT | |
| SCHEMBL12294725 | 0.78 | HRH3 (0.48) | ST14NCF1ALDH1A1HTTMAPT | |
| SCHEMBL2883585 | 0.77 | LTA4H (0.67) | RAB9AALDH1A1HTTMAPTNPC1 | |
| SCHEMBL18415522 | 0.77 | AKR1C3 (0.62) | RAB9AALDH1A1HTTMAPTMEN1 | |
| SCHEMBL15867084 | 0.77 | MAPK1 (0.57) | RAB9AALDH1A1HTTMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078370-A1 | NOVEL PARABANIC ACID DERIVATIVE AND DRUG HAVING THE SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |