Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922869 | 0.84 | L3MBTL1 (0.50) | L3MBTL1KDM4EPKMSMN1; SMN2MAPK1 | |
| SCHEMBL4616208 | 0.82 | L3MBTL1 (0.77) | L3MBTL1KDM4EPKMSMN1; SMN2MAPK1 | |
| SCHEMBL22700981 | 0.80 | LMNA (0.53) | L3MBTL1KDM4EPKMSMN1; SMN2POLB | |
| SCHEMBL2916194 | 0.78 | L3MBTL1 (0.70) | L3MBTL1KDM4EPKMSMN1; SMN2MAPK1 | |
| SCHEMBL1263701 | 0.77 | MAPT (0.46) | L3MBTL1KDM4EPKMSMN1; SMN2MAPK1 | |
| SCHEMBL1263700 | 0.77 | MAPT (0.46) | L3MBTL1KDM4EPKMSMN1; SMN2MAPK1 | |
| SCHEMBL1223439 | 0.76 | P2RX4 (0.68) | KDM4ESMN1; SMN2MAPK1POLBLMNA | |
| SCHEMBL3034960 | 0.74 | L3MBTL1 (0.60) | L3MBTL1KDM4EPKMSMN1; SMN2MAPK1 | |
| SCHEMBL29405472 | 0.74 | CYP19A1 (0.63) | KDM4EPOLBLMNAUSP2PSMD14 | |
| SCHEMBL30681661 | 0.74 | CYP19A1 (0.63) | KDM4EPOLBLMNAUSP2PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435696-B2 | Redox-active polymers and their applications | BROWN UNIVERSITY (US) | 2013-05-07 | — | — | US | disclosed |