Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | APAF1 | O14727 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | ECE1 | P42892 | 7/20 | 0.71 |
| ▸ | ACE | P12821 | 3/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.63 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.63 |
| ▸ | ITGAL | P20701 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.61 |
| ▸ | FPR2 | P25090 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263822 | 1.00 | KDM4E (0.72) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL19737124 | 0.92 | ACE (0.70) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL15592745 | 0.92 | ACE (0.70) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL16750046 | 0.92 | ACE (0.70) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL8254531 | 0.91 | ACE (0.68) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL5870457 | 0.91 | ACE (0.68) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL7201046 | 0.90 | ACE (0.67) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL29114797 | 0.88 | ACE (0.65) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL7222741 | 0.88 | ALOX15 (0.66) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL170877 | 0.87 | KDM4E (0.69) | KDM4EMAPTAPAF1POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879791-B2 | for supplementing antiretroviral HIV therapy; regulation via cytokines such as macrophage colony stimulating factor, interferon gamma, with antigen; sustained release patches | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2011-02-01 | — | — | US | disclosed |